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    GPER1 G protein-coupled estrogen receptor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696625, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GPER1provided by VGNC
    Official Full Name
    G protein-coupled estrogen receptor 1provided by VGNC
    Primary source
    VGNC:VGNC:73132
    Locus tag
    EGK_13399
    See related
    Ensembl:ENSMMUG00000007209
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    GPER; GPR30
    Orthologs
    human mouse all
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    Genomic context

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    See GPER1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (34152141..34159826)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (35006025..35011364)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene chromosome 3 C7orf50 homolog Neighboring gene microRNA mir-339 Neighboring gene G protein-coupled receptor 146 Neighboring gene zinc finger AN1-type containing 2A Neighboring gene UNC homeobox

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diverse Synaptic Distributions of G Protein-coupled Estrogen Receptor 1 in Monkey Prefrontal Cortex with Aging and Menopause. Crimins JL, et al. Cereb Cortex, 2017 Mar 1. PMID 26941383, Free PMC Article
    2. Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons. Noel SD, et al. Mol Endocrinol, 2009 Mar. PMID 19131510, Free PMC Article
    3. Evolutionary and biomedical insights from the rhesus macaque genome. Rhesus Macaque Genome Sequencing and Analysis Consortium, et al. Science, 2007 Apr 13. PMID 17431167
    4. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    5. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Study demonstrated that GPER1 is ideally positioned to support diverse functions important to the modulation of synaptic plasticity in monkey dorsolateral prefrontal cortex with aging and menopause
      Title: Diverse Synaptic Distributions of G Protein-coupled Estrogen Receptor 1 in Monkey Prefrontal Cortex with Aging and Menopause.
    2. Estradiol(E2) induces a rapid excitatory effect on primate LHRH neurons, and this rapid action of E2 appears to be mediated, in part, through GPR30.
      Title: Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G-protein coupled estrogen receptor 1
    Names
    G protein-coupled receptor 30

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      34152141..34159826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028845477.1 → XP_028701310.1  G-protein coupled estrogen receptor 1

      UniProtKB/Swiss-Prot
      F7EQ49
      Related
      ENSMMUP00000009453.3, ENSMMUT00000010070.3
      Conserved Domains (1) summary
      cd14989
      Location:60 → 335
      7tmA_GPER1; G protein-coupled estrogen receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_001084531.4 → XP_001084531.1  G-protein coupled estrogen receptor 1

      See identical proteins and their annotated locations for XP_001084531.1

      UniProtKB/Swiss-Prot
      F7EQ49
      Related
      ENSMMUP00000049453.1, ENSMMUT00000070839.2
      Conserved Domains (1) summary
      cd14989
      Location:60 → 335
      7tmA_GPER1; G protein-coupled estrogen receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F7EQ49.1 GenPept UniProtKB/Swiss-Prot:F7EQ49

    Gene LinkOut

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