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    Slc6a16 solute carrier family 6, member 16 [ Mus musculus (house mouse) ]

    Gene ID: 381884, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc6a16provided by MGI
    Official Full Name
    solute carrier family 6, member 16provided by MGI
    Primary source
    MGI:MGI:2685930
    See related
    Ensembl:ENSMUSG00000094152 AllianceGenome:MGI:2685930
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1084
    Summary
    Predicted to be involved in amino acid transport and sodium ion transmembrane transport. Predicted to be active in plasma membrane. Orthologous to human SLC6A16 (solute carrier family 6 member 16). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 27.4) See more
    Orthologs
    human all
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    Genomic context

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    See Slc6a16 in Genome Data Viewer
    Location:
    7 B3; 7 29.22 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44890177..44922789)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45240753..45273365)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene TEA domain family member 2 Neighboring gene STARR-seq mESC enhancer starr_18834 Neighboring gene STARR-positive B cell enhancer ABC_E872 Neighboring gene STARR-seq mESC enhancer starr_18835 Neighboring gene CD37 antigen Neighboring gene predicted gene, 23585 Neighboring gene solute carrier family 6 member 21 Neighboring gene STARR-positive B cell enhancer ABC_E6543 Neighboring gene predicted gene, 39006

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Gene trapped (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001324535.1 → NP_001311464.1  orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

      Status: PROVISIONAL

      Source sequence(s)
      AC150897
      Consensus CDS
      CCDS90233.1
      UniProtKB/TrEMBL
      A0A1L1SR47, A0A1L1SVE2
      Related
      ENSMUSP00000149306.2, ENSMUST00000213347.2
      Conserved Domains (1) summary
      cl00456
      Location:125 → 694
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      44890177..44922789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153198.1 → XP_036009091.1  orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 isoform X1

      UniProtKB/TrEMBL
      A0A1L1SVE2
      Conserved Domains (1) summary
      cl00456
      Location:125 → 612
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein
    Heading Accession and Version

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