Atp5mc2 ATP synthase membrane subunit c locus 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Atp5mc2provided by MGI
Official Full Name: ATP synthase membrane subunit c locus 2provided by MGI
Primary source: MGI:MGI:1915192
See related: Ensembl:ENSMUSG00000062683 AllianceGenome:MGI:1915192
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Atp5g2; 1810041M08Rik
Summary: Predicted to enable ligand-gated channel activity. Predicted to be involved in pore complex assembly and proton motive force-driven ATP synthesis. Located in mitochondrion. Is expressed in several structures, including alimentary system; eye; genitourinary system; heart; and nervous system. Human ortholog(s) of this gene implicated in renal cell carcinoma and urinary bladder cancer. Orthologous to human ATP5MC2 (ATP synthase membrane subunit c locus 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in colon adult (RPKM 306.9), kidney adult (RPKM 301.2) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 F3; 15 57.77 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (102571303..102579482, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (102662868..102671047, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ligand-gated channel activity	ISO Inferred from Sequence Orthology more info
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables proton transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in pore complex assembly	ISO Inferred from Sequence Orthology more info
involved_in proton motive force-driven ATP synthesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in proton motive force-driven ATP synthesis	IEA Inferred from Electronic Annotation more info
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of cation channel complex	ISO Inferred from Sequence Orthology more info
located_in mitochondrial membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
part_of proton-transporting ATP synthase complex, coupling factor F(o)	IBA Inferred from Biological aspect of Ancestor more info
part_of proton-transporting ATP synthase complex, coupling factor F(o)	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATP synthase F(0) complex subunit C2, mitochondrial

Names: ATP synthase lipid-binding protein, mitochondrial; ATP synthase proteolipid P2; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9); ATPase protein 9; ATPase subunit c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.