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    GABRA3 gamma-aminobutyric acid type A receptor subunit alpha3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711230, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GABRA3provided by VGNC
    Official Full Name
    gamma-aminobutyric acid type A receptor subunit alpha3provided by VGNC
    Primary source
    VGNC:VGNC:72848
    Locus tag
    EGK_21055
    See related
    Ensembl:ENSMMUG00000001540
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GABRA3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (148167848..148453456, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (145797940..145915488, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106995361 Neighboring gene MAGE family member A10 Neighboring gene U6 spliceosomal RNA Neighboring gene microRNA mir-105-1 Neighboring gene microRNA mir-105-2 Neighboring gene microRNA mir-767 Neighboring gene keratin, type II cytoskeletal 8 pseudogene Neighboring gene gamma-aminobutyric acid type A receptor subunit theta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GABA-A receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GABA-gated chloride ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables benzodiazepine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables inhibitory extracellular ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloride transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gamma-aminobutyric acid signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, GABAergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of GABA-A receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma-aminobutyric acid receptor subunit alpha-3
    Names
    gamma-aminobutyric acid type A receptor alpha3 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      148167848..148453456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028841930.1 → XP_028697763.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X2

      Conserved Domains (3) summary
      TIGR00860
      Location:1 → 369
      LIC; Cation transporter family protein
      cd03558
      Location:82 → 96
      LGIC_ECD; Cys-loop [structural motif]
      cl28912
      Location:1 → 165
      LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

    2. XM_028841929.1 → XP_028697762.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X1

      UniProtKB/TrEMBL
      A0A5S6R9G9, A0A8J8Y806, F7G8R5, G7NRZ9, H9FSG4
      Related
      ENSMMUP00000002056.4, ENSMMUT00000002176.4
      Conserved Domains (2) summary
      TIGR00860
      Location:69 → 478
      LIC; Cation transporter family protein
      cd19036
      Location:75 → 274
      LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

    3. XM_028841928.1 → XP_028697761.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X1

      UniProtKB/TrEMBL
      A0A5S6R9G9, A0A8J8Y806, F7G8R5, G7NRZ9, H9FSG4
      Related
      ENSMMUP00000070695.1, ENSMMUT00000105647.1
      Conserved Domains (2) summary
      TIGR00860
      Location:69 → 478
      LIC; Cation transporter family protein
      cd19036
      Location:75 → 274
      LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)
    Nucleotide Protein
    Heading Accession and Version

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