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    TFRC transferrin receptor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711568, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TFRCprovided by VGNC
    Official Full Name
    transferrin receptorprovided by VGNC
    Primary source
    VGNC:VGNC:78330
    See related
    Ensembl:ENSMMUG00000002114
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TFRC in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (795620..828939, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (202670211..202705095, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676118 Neighboring gene uncharacterized LOC114676192 Neighboring gene U7 small nuclear RNA Neighboring gene RAF proto-oncogene serine/threonine-protein kinase-like Neighboring gene uncharacterized LOC114676193 Neighboring gene zinc finger DHHC-type palmitoyltransferase 19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis. Koppensteiner H, et al. Retrovirology, 2014 Jan 2. PMID 24383984, Free PMC Article
    2. An antibody recognizing the apical domain of human transferrin receptor 1 efficiently inhibits the entry of all new world hemorrhagic Fever arenaviruses. Helguera G, et al. J Virol, 2012 Apr. PMID 22278244, Free PMC Article
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transferrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transferrin transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transferrin receptor protein 1
    Names
    transferrin receptor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257303.1 → NP_001244232.1  transferrin receptor protein 1

      See identical proteins and their annotated locations for NP_001244232.1

      Status: PROVISIONAL

      Source sequence(s)
      JQ014204
      UniProtKB/TrEMBL
      F6UX47, I0FKY7
      Conserved Domains (3) summary
      cd09848
      Location:385 → 610
      M28_TfR; M28 Zn-peptidase Transferrin Receptor family
      cd02128
      Location:201 → 377
      PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
      pfam04253
      Location:642 → 750
      TFR_dimer; Transferrin receptor-like dimerization domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      795620..828939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015132553.2 → XP_014988039.1  transferrin receptor protein 1 isoform X1

      UniProtKB/TrEMBL
      F6UX47, I0FKY7
      Related
      ENSMMUP00000002816.2, ENSMMUT00000002982.4
      Conserved Domains (3) summary
      cd09848
      Location:385 → 610
      M28_TfR; M28 Zn-peptidase Transferrin Receptor family
      cd02128
      Location:201 → 377
      PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
      pfam04253
      Location:642 → 750
      TFR_dimer; Transferrin receptor-like dimerization domain
    Nucleotide Protein
    Heading Accession and Version

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