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    FANCL FA complementation group L [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717528, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FANCLprovided by VGNC
    Official Full Name
    FA complementation group Lprovided by VGNC
    Primary source
    VGNC:VGNC:72542
    See related
    Ensembl:ENSMMUG00000002026
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    VRK2
    Orthologs
    human mouse all
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    Genomic context

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    See FANCL in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (50524108..50608400)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (59026357..59111116, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106992963 Neighboring gene uncharacterized LOC106992962 Neighboring gene VRK serine/threonine kinase 2 Neighboring gene SMT3 suppressor of mif two 3 homolog 3-like Neighboring gene small nucleolar RNA SNORD78

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interstrand cross-link repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein monoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Fanconi anaemia nuclear complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase FANCL
    Names
    Fanconi anemia complementation group L
    serine/threonine-protein kinase VRK2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      50524108..50608400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015112413.2 → XP_014967899.2  E3 ubiquitin-protein ligase FANCL isoform X1

      UniProtKB/TrEMBL
      A0A1D5RER3
      Conserved Domains (3) summary
      pfam09765
      Location:101 → 386
      WD-3; WD-repeat region
      pfam11793
      Location:394 → 462
      FANCL_C; FANCL C-terminal domain
      cd16490
      Location:398 → 453
      RING-CH-C4HC3_FANCL; RING-CH finger (C4HC3-type) [structural motif]

    2. XM_001115119.4 → XP_001115119.4  E3 ubiquitin-protein ligase FANCL isoform X2

      UniProtKB/TrEMBL
      A0A1D5RER3
      Related
      ENSMMUP00000058806.2, ENSMMUT00000076873.2
      Conserved Domains (3) summary
      pfam09765
      Location:101 → 381
      WD-3; WD-repeat region
      pfam11793
      Location:389 → 457
      FANCL_C; FANCL C-terminal domain
      cd16490
      Location:393 → 448
      RING-CH-C4HC3_FANCL; RING-CH finger (C4HC3-type) [structural motif]

    3. XM_028832469.1 → XP_028688302.1  E3 ubiquitin-protein ligase FANCL isoform X3

      Conserved Domains (3) summary
      pfam09765
      Location:101 → 327
      WD-3; WD-repeat region
      pfam11793
      Location:335 → 403
      FANCL_C; FANCL C-terminal domain
      cd16490
      Location:339 → 394
      RING-CH-C4HC3_FANCL; RING-CH finger (C4HC3-type) [structural motif]

    4. XM_028832470.1 → XP_028688303.1  E3 ubiquitin-protein ligase FANCL isoform X4

      Conserved Domains (3) summary
      pfam09765
      Location:101 → 322
      WD-3; WD-repeat region
      pfam11793
      Location:330 → 398
      FANCL_C; FANCL C-terminal domain
      cd16490
      Location:334 → 389
      RING-CH-C4HC3_FANCL; RING-CH finger (C4HC3-type) [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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