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    MGMT O-6-methylguanine-DNA methyltransferase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698134, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MGMTprovided by VGNC
    Official Full Name
    O-6-methylguanine-DNA methyltransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:74717
    See related
    Ensembl:ENSMMUG00000011446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MGMT in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (129903078..130194536)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (125641174..125933351)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000309 Neighboring gene uncharacterized LOC114670071 Neighboring gene uncharacterized LOC114670072 Neighboring gene uncharacterized LOC107000310 Neighboring gene uncharacterized LOC114670070

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables methylated-DNA-[protein]-cysteine S-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methylated-DNA--protein-cysteine methyltransferase
    NP_001244534.1
    XP_028709148.1
    XP_028709149.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257605.2 → NP_001244534.1  methylated-DNA--protein-cysteine methyltransferase

      See identical proteins and their annotated locations for NP_001244534.1

      Status: PROVISIONAL

      Source sequence(s)
      JU323468
      UniProtKB/TrEMBL
      F7B443, G7N1E3, H9EXW5
      Related
      ENSMMUP00000015013.3, ENSMMUT00000016020.4
      Conserved Domains (3) summary
      COG0350
      Location:38 → 204
      AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
      TIGR00589
      Location:124 → 203
      ogt; O-6-methylguanine DNA methyltransferase
      pfam02870
      Location:37 → 121
      Methyltransf_1N; 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      129903078..130194536
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028853315.1 → XP_028709148.1  methylated-DNA--protein-cysteine methyltransferase isoform X1

      UniProtKB/TrEMBL
      G7N1E3
      Conserved Domains (2) summary
      COG0350
      Location:7 → 173
      AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
      TIGR00589
      Location:93 → 172
      ogt; O-6-methylguanine DNA methyltransferase

    2. XM_028853316.1 → XP_028709149.1  methylated-DNA--protein-cysteine methyltransferase isoform X1

      UniProtKB/TrEMBL
      G7N1E3
      Conserved Domains (2) summary
      COG0350
      Location:7 → 173
      AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
      TIGR00589
      Location:93 → 172
      ogt; O-6-methylguanine DNA methyltransferase
    Nucleotide Protein
    Heading Accession and Version

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