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    EFS embryonal Fyn-associated substrate [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713838, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EFSprovided by VGNC
    Official Full Name
    embryonal Fyn-associated substrateprovided by VGNC
    Primary source
    VGNC:VGNC:72056
    See related
    Ensembl:ENSMMUG00000014750
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EFS in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (85398272..85408171, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (84709191..84718671, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene polyadenylate-binding protein 2 Neighboring gene solute carrier family 22 member 17 Neighboring gene interleukin 25 Neighboring gene CKLF like MARVEL transmembrane domain containing 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    embryonal Fyn-associated substrate

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      85398272..85408171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015143405.2 → XP_014998891.2  embryonal Fyn-associated substrate isoform X2

      UniProtKB/TrEMBL
      F7G472, G7MX45
      Related
      ENSMMUP00000019362.3, ENSMMUT00000020690.4
      Conserved Domains (2) summary
      cd12003
      Location:8 → 70
      SH3_EFS; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Embryonal Fyn-associated Substrate
      cl13463
      Location:372 → 503
      FAT-like_CAS_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module

    2. XM_001107716.4 → XP_001107716.2  embryonal Fyn-associated substrate isoform X1

      UniProtKB/TrEMBL
      G7MX45, H9FNL6
      Related
      ENSMMUP00000019363.4, ENSMMUT00000020691.4
      Conserved Domains (2) summary
      cd12003
      Location:8 → 70
      SH3_EFS; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Embryonal Fyn-associated Substrate
      pfam12026
      Location:372 → 556
      DUF3513; Domain of unknown function (DUF3513)

    3. XM_015143406.2 → XP_014998892.2  embryonal Fyn-associated substrate isoform X4

      UniProtKB/TrEMBL
      G7MX45
      Conserved Domains (2) summary
      cd12003
      Location:8 → 70
      SH3_EFS; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Embryonal Fyn-associated Substrate
      pfam12026
      Location:290 → 474
      DUF3513; Domain of unknown function (DUF3513)

    4. XM_028851430.1 → XP_028707263.1  embryonal Fyn-associated substrate isoform X3

      UniProtKB/TrEMBL
      G7MX45
      Conserved Domains (2) summary
      cd12003
      Location:8 → 70
      SH3_EFS; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Embryonal Fyn-associated Substrate
      cl13463
      Location:372 → 503
      FAT-like_CAS_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module
    Nucleotide Protein
    Heading Accession and Version

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