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    XPNPEP1 X-prolyl aminopeptidase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696570, updated on 17-Aug-2024

    Summary

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    Official Symbol
    XPNPEP1provided by VGNC
    Official Full Name
    X-prolyl aminopeptidase 1provided by VGNC
    Primary source
    VGNC:VGNC:78810
    Locus tag
    EGK_20054
    See related
    Ensembl:ENSMMUG00000015117
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See XPNPEP1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (110401632..110462795, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (105730181..105795441, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene prohibitin-2 pseudogene Neighboring gene putative uncharacterized protein encoded by LINC00269 Neighboring gene small nucleolar RNA SNORA18 Neighboring gene basic proline-rich protein-like Neighboring gene adducin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    xaa-Pro aminopeptidase 1
    NP_001253891.1
    XP_015003603.1
    XP_015003604.1
    XP_015003606.1
    XP_015003607.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266962.1 → NP_001253891.1  xaa-Pro aminopeptidase 1

      See identical proteins and their annotated locations for NP_001253891.1

      Status: PROVISIONAL

      Source sequence(s)
      JU477095
      UniProtKB/TrEMBL
      H9ZD83, I0FUX1
      Related
      ENSMMUP00000019817.4, ENSMMUT00000021191.4
      Conserved Domains (4) summary
      cd01085
      Location:372 → 594
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam01321
      Location:53 → 197
      Creatinase_N; Creatinase/Prolidase N-terminal domain
      pfam16188
      Location:600 → 662
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:200 → 369
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      110401632..110462795 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148121.2 → XP_015003607.1  xaa-Pro aminopeptidase 1 isoform X2

      UniProtKB/TrEMBL
      F7DGY1, F7DGZ3, G7N139
      Conserved Domains (3) summary
      cd01085
      Location:258 → 480
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:486 → 548
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:86 → 255
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain

    2. XM_015148118.2 → XP_015003604.1  xaa-Pro aminopeptidase 1 isoform X1

      UniProtKB/TrEMBL
      A0A5K1VLA5, A0A5K1VLA6, A0A8J8YAX7, I0FUX1
      Related
      ENSMMUP00000064521.1, ENSMMUT00000089756.1
      Conserved Domains (4) summary
      cd01085
      Location:329 → 551
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam01321
      Location:10 → 154
      Creatinase_N; Creatinase/Prolidase N-terminal domain
      pfam16188
      Location:557 → 619
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:157 → 326
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain

    3. XM_015148120.2 → XP_015003606.1  xaa-Pro aminopeptidase 1 isoform X2

      UniProtKB/TrEMBL
      F7DGY1, F7DGZ3, G7N139
      Related
      ENSMMUP00000035652.3, ENSMMUT00000042644.3
      Conserved Domains (3) summary
      cd01085
      Location:258 → 480
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:486 → 548
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:86 → 255
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain

    4. XM_015148117.2 → XP_015003603.1  xaa-Pro aminopeptidase 1 isoform X1

      UniProtKB/TrEMBL
      A0A5K1VLA5, A0A5K1VLA6, A0A8J8YAX7, I0FUX1
      Related
      ENSMMUP00000019818.4, ENSMMUT00000021192.4
      Conserved Domains (4) summary
      cd01085
      Location:329 → 551
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam01321
      Location:10 → 154
      Creatinase_N; Creatinase/Prolidase N-terminal domain
      pfam16188
      Location:557 → 619
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:157 → 326
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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