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    TDP2 tyrosyl-DNA phosphodiesterase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715162, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TDP2provided by VGNC
    Official Full Name
    tyrosyl-DNA phosphodiesterase 2provided by VGNC
    Primary source
    VGNC:VGNC:78403
    See related
    Ensembl:ENSMMUG00000009803
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TDP2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (145320594..145338418)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (25186203..25204007, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene chromosome 4 C6orf62 homolog Neighboring gene uncharacterized LOC114677680 Neighboring gene acyl-CoA thioesterase 13 Neighboring gene KIAA0319 Neighboring gene uncharacterized LOC106997846 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene 60S ribosomal protein L7a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5'-tyrosyl-DNA phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in PML body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosyl-DNA phosphodiesterase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      145320594..145338418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001105245.4 → XP_001105245.3  tyrosyl-DNA phosphodiesterase 2

      UniProtKB/TrEMBL
      F6PMX6, G8F1A8, H9FVM3
      Related
      ENSMMUP00000034355.3, ENSMMUT00000041324.3
      Conserved Domains (2) summary
      cd09080
      Location:142 → 384
      TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
      cd14344
      Location:53 → 89
      UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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