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    ACACA acetyl-CoA carboxylase alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714218, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ACACAprovided by VGNC
    Official Full Name
    acetyl-CoA carboxylase alphaprovided by VGNC
    Primary source
    VGNC:VGNC:69592
    Locus tag
    EGK_08623
    See related
    Ensembl:ENSMMUG00000009349
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ACACA in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    56
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (33694162..34022054)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (43101168..43432092, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106994025 Neighboring gene transcriptional adaptor 2A Neighboring gene chromosome 16 C17orf78 homolog Neighboring gene 60S ribosomal protein L17-like Neighboring gene uncharacterized LOC106994024 Neighboring gene 60S ribosomal protein L18a pseudogene Neighboring gene high mobility group protein B1 pseudogene Neighboring gene uncharacterized LOC106994023 Neighboring gene apoptosis antagonizing transcription factor Neighboring gene uncharacterized LOC106994020 Neighboring gene LIM homeobox 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables acetyl-CoA carboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acetyl-CoA carboxylase 1
    NP_001253707.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266778.1 → NP_001253707.1  acetyl-CoA carboxylase 1 precursor

      See identical proteins and their annotated locations for NP_001253707.1

      Status: PROVISIONAL

      Source sequence(s)
      JU322287
      UniProtKB/TrEMBL
      A0A8J8YPD6, F7H9H5, F7HHF7, H9EUI4
      Related
      ENSMMUP00000012251.4, ENSMMUT00000013071.4
      Conserved Domains (5) summary
      COG0439
      Location:155 → 657
      AccC; Biotin carboxylase [Lipid transport and metabolism]
      pfam00364
      Location:790 → 855
      Biotin_lipoyl; Biotin-requiring enzyme
      pfam01039
      Location:1706 → 2254
      Carboxyl_trans; Carboxyl transferase domain
      pfam08326
      Location:857 → 1599
      ACC_central; Acetyl-CoA carboxylase, central region
      cl27427
      Location:708 → 855
      AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      33694162..34022054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials