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    PARD6A par-6 family cell polarity regulator alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699351, updated on 17-Aug-2024

    Summary

    Official Symbol
    PARD6Aprovided by VGNC
    Official Full Name
    par-6 family cell polarity regulator alphaprovided by VGNC
    Primary source
    VGNC:VGNC:104743
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See PARD6A in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (54856947..54858797)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (51996287..51998388)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene CCCTC-binding factor Neighboring gene capping protein regulator and myosin 1 linker 2 Neighboring gene chromosome 20 C16orf86 homolog Neighboring gene ACD shelterin complex subunit and telomerase recruitment factor Neighboring gene enkurin domain containing 1 Neighboring gene Gfo/Idh/MocA-like oxidoreductase domain containing 2

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein kinase C binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in centrosome cycle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in establishment or maintenance of cell polarity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of cellular localization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    partitioning defective 6 homolog alpha
    Names
    par-6 partitioning defective 6 homolog alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266564.2NP_001253493.1  partitioning defective 6 homolog alpha

      See identical proteins and their annotated locations for NP_001253493.1

      Status: PROVISIONAL

      Source sequence(s)
      JV667407
      UniProtKB/TrEMBL
      G7NQ63, I2CYN5
      Conserved Domains (2) summary
      cd06403
      Location:1695
      PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
      cd00992
      Location:156247
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      54856947..54858797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126410.2XP_014981896.2  partitioning defective 6 homolog alpha isoform X1

      UniProtKB/TrEMBL
      G7NQ63
      Conserved Domains (2) summary
      cd06403
      Location:1695
      PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
      cd00992
      Location:155246
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...