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    NPAS4 neuronal PAS domain protein 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714161, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NPAS4provided by VGNC
    Official Full Name
    neuronal PAS domain protein 4provided by VGNC
    Primary source
    VGNC:VGNC:75211
    See related
    Ensembl:ENSMMUG00000015982
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NPAS4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (8131388..8137081, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (8004905..8010599, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L11 Neighboring gene small nucleolar RNA SNORA43 Neighboring gene uncharacterized LOC106993186 Neighboring gene U1 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuronal PAS domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      8131388..8137081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028833208.1 → XP_028689041.1  neuronal PAS domain-containing protein 4 isoform X5

    2. XM_001110331.3 → XP_001110331.1  neuronal PAS domain-containing protein 4 isoform X2

      See identical proteins and their annotated locations for XP_001110331.1

      UniProtKB/TrEMBL
      F6XNH5, G7NC59
      Related
      ENSMMUP00000021022.4, ENSMMUT00000022472.4
      Conserved Domains (3) summary
      smart00091
      Location:72 → 135
      PAS; PAS domain
      pfam08447
      Location:228 → 296
      PAS_3; PAS fold
      cd19697
      Location:2 → 57
      bHLH-PAS_NPAS4_PASD10; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 4 (NPAS4) and similar proteins

    3. XM_015113638.2 → XP_014969124.1  neuronal PAS domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      G7NC59
      Conserved Domains (4) summary
      smart00091
      Location:72 → 135
      PAS; PAS domain
      cd00130
      Location:214 → 294
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
      pfam08447
      Location:95 → 188
      PAS_3; PAS fold
      pfam14598
      Location:217 → 319
      PAS_11; PAS domain

    4. XM_015113639.2 → XP_014969125.1  neuronal PAS domain-containing protein 4 isoform X3

    5. XM_028833207.1 → XP_028689040.1  neuronal PAS domain-containing protein 4 isoform X4

    Nucleotide Protein
    Heading Accession and Version

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