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    IRX1 iroquois homeobox 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693825, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IRX1provided by VGNC
    Official Full Name
    iroquois homeobox 1provided by VGNC
    Primary source
    VGNC:VGNC:73591
    See related
    Ensembl:ENSMMUG00000002613
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IRX1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (3541464..3547046)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (3464269..3469829)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial pseudogene Neighboring gene uncharacterized LOC114678733 Neighboring gene uncharacterized LOC106998639 Neighboring gene uncharacterized LOC106998640 Neighboring gene uncharacterized LOC114678734

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    iroquois-class homeodomain protein IRX-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      3541464..3547046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001082149.4 → XP_001082149.1  iroquois-class homeodomain protein IRX-1

      See identical proteins and their annotated locations for XP_001082149.1

      UniProtKB/TrEMBL
      A0A5F7ZE04, A0A5F7ZLF9
      Related
      ENSMMUP00000063817.1, ENSMMUT00000084142.1
      Conserved Domains (3) summary
      smart00548
      Location:309 → 326
      IRO; Motif in Iroquois-class homeodomain proteins (only). Unknown function
      pfam05920
      Location:145 → 184
      Homeobox_KN; Homeobox KN domain
      cl01319
      Location:188 → 247
      HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    Nucleotide Protein
    Heading Accession and Version

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