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    EGR2 early growth response 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698132, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EGR2provided by VGNC
    Official Full Name
    early growth response 2provided by VGNC
    Primary source
    VGNC:VGNC:72174
    Locus tag
    EGK_19824
    See related
    Ensembl:ENSMMUG00000010256
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EGR2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (75154129..75158502)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (69903509..69907892)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000186 Neighboring gene uncharacterized LOC114670134 Neighboring gene 2-aminoethanethiol dioxygenase Neighboring gene talanin-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 SUMO-protein ligase EGR2
    Names
    early growth response 2 (Krox-20 homolog, Drosophila)
    early growth response protein 2
    NP_001245015.1
    XP_015003019.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001258086.1 → NP_001245015.1  E3 SUMO-protein ligase EGR2

      See identical proteins and their annotated locations for NP_001245015.1

      Status: PROVISIONAL

      Source sequence(s)
      JU471706
      UniProtKB/TrEMBL
      A0A5S6R8E0, A0A8J8XBH1, F6QLX6, G7N2E2
      Related
      ENSMMUP00000013427.4, ENSMMUT00000014337.4
      Conserved Domains (4) summary
      COG5048
      Location:368 → 436
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:342 → 364
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:340 → 364
      zf-C2H2; Zinc finger, C2H2 type
      pfam11928
      Location:94 → 166
      DUF3446; Domain of unknown function (DUF3446)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      75154129..75158502
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015147533.2 → XP_015003019.1  E3 SUMO-protein ligase EGR2 isoform X1

      UniProtKB/TrEMBL
      F6QLX6
      Conserved Domains (5) summary
      COG5048
      Location:310 → 378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:284 → 306
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:282 → 306
      zf-C2H2; Zinc finger, C2H2 type
      pfam11928
      Location:36 → 108
      DUF3446; Domain of unknown function (DUF3446)
      pfam13465
      Location:326 → 351
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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