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    MYO6 myosin VI [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716634, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MYO6provided by VGNC
    Official Full Name
    myosin VIprovided by VGNC
    Primary source
    VGNC:VGNC:75118
    See related
    Ensembl:ENSMMUG00000005032
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    myosin-VI
    Orthologs
    human mouse all
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    Genomic context

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    See MYO6 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (97096230..97260374, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (73865975..74037622)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene interphotoreceptor matrix proteoglycan 1 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC114677561 Neighboring gene SUMO specific peptidase 6 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microfilament motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inner ear auditory receptor cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inner ear morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle transport along actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endocytic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ruffle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    unconventional myosin-VI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104536.1 → NP_001098006.1  unconventional myosin-VI

      See identical proteins and their annotated locations for NP_001098006.1

      Status: PROVISIONAL

      Source sequence(s)
      EU073749
      UniProtKB/TrEMBL
      A7XBL5, G7MPR9
      Conserved Domains (3) summary
      smart00242
      Location:52 → 771
      MYSc; Myosin. Large ATPases
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1136 → 1226
      Myosin-VI_CBD; Myosin VI cargo binding domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      97096230..97260374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136777.2 → XP_014992263.1  unconventional myosin-VI isoform X8

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (3) summary
      smart00242
      Location:52 → 771
      MYSc; Myosin. Large ATPases
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1145 → 1235
      Myosin-VI_CBD; Myosin VI cargo binding domain

    2. XM_015136778.2 → XP_014992264.1  unconventional myosin-VI isoform X9

      UniProtKB/TrEMBL
      A0A1D5QGD8, G7MPR9
      Related
      ENSMMUP00000047108.2, ENSMMUT00000072194.2
      Conserved Domains (3) summary
      smart00242
      Location:52 → 771
      MYSc; Myosin. Large ATPases
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1136 → 1226
      Myosin-VI_CBD; Myosin VI cargo binding domain

    3. XM_015136776.2 → XP_014992262.1  unconventional myosin-VI isoform X7

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (3) summary
      smart00242
      Location:52 → 771
      MYSc; Myosin. Large ATPases
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1155 → 1245
      Myosin-VI_CBD; Myosin VI cargo binding domain

    4. XM_015136775.2 → XP_014992261.1  unconventional myosin-VI isoform X5

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (3) summary
      smart00242
      Location:52 → 771
      MYSc; Myosin. Large ATPases
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1159 → 1249
      Myosin-VI_CBD; Myosin VI cargo binding domain

    5. XM_015136773.2 → XP_014992259.1  unconventional myosin-VI isoform X3

      UniProtKB/TrEMBL
      F7ARX1, G7MPR9
      Related
      ENSMMUP00000006662.4, ENSMMUT00000007091.4
      Conserved Domains (4) summary
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam05835
      Location:980 → 1055
      Synaphin; Synaphin protein
      pfam16521
      Location:1168 → 1258
      Myosin-VI_CBD; Myosin VI cargo binding domain
      cl25732
      Location:846 → 1134
      SMC_N; RecF/RecN/SMC N terminal domain

    6. XM_028846843.1 → XP_028702676.1  unconventional myosin-VI isoform X6

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (2) summary
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1155 → 1245
      Myosin-VI_CBD; Myosin VI cargo binding domain

    7. XM_015136774.2 → XP_014992260.1  unconventional myosin-VI isoform X4

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (3) summary
      smart00242
      Location:52 → 771
      MYSc; Myosin. Large ATPases
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1164 → 1254
      Myosin-VI_CBD; Myosin VI cargo binding domain

    8. XM_015136772.2 → XP_014992258.1  unconventional myosin-VI isoform X2

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (3) summary
      smart00242
      Location:52 → 771
      MYSc; Myosin. Large ATPases
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1168 → 1258
      Myosin-VI_CBD; Myosin VI cargo binding domain

    9. XM_015136770.2 → XP_014992256.1  unconventional myosin-VI isoform X1

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (4) summary
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1177 → 1267
      Myosin-VI_CBD; Myosin VI cargo binding domain
      cd21759
      Location:770 → 917
      CBD_MYO6-like; calmodulin binding domain found in unconventional myosin-VI and similar proteins
      cd22294
      Location:999 → 1068
      MYO6_MIU_linker; MIU-linker domain found in unconventional myosin-VI

    10. XM_028846844.1 → XP_028702677.1  unconventional myosin-VI isoform X10

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (2) summary
      pfam16521
      Location:930 → 1020
      Myosin-VI_CBD; Myosin VI cargo binding domain
      cl22853
      Location:3 → 512
      Motor_domain; Myosin and Kinesin motor domain

    11. XM_015136771.2 → XP_014992257.1  unconventional myosin-VI isoform X1

      UniProtKB/TrEMBL
      G7MPR9
      Conserved Domains (4) summary
      cd01382
      Location:71 → 759
      MYSc_Myo6; class VI myosin, motor domain
      pfam16521
      Location:1177 → 1267
      Myosin-VI_CBD; Myosin VI cargo binding domain
      cd21759
      Location:770 → 917
      CBD_MYO6-like; calmodulin binding domain found in unconventional myosin-VI and similar proteins
      cd22294
      Location:999 → 1068
      MYO6_MIU_linker; MIU-linker domain found in unconventional myosin-VI
    Nucleotide Protein
    Heading Accession and Version

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