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    LIN7A lin-7 homolog A, crumbs cell polarity complex component [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697557, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LIN7Aprovided by VGNC
    Official Full Name
    lin-7 homolog A, crumbs cell polarity complex componentprovided by VGNC
    Primary source
    VGNC:VGNC:74068
    See related
    Ensembl:ENSMMUG00000011671
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LIN7A in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (80319701..80471918, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (79678344..79831184, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene myogenic factor 5 Neighboring gene uncharacterized LOC107000955 Neighboring gene uncharacterized LOC114670904 Neighboring gene microRNA mir-618 Neighboring gene uncharacterized LOC107000949 Neighboring gene nucleophosmin pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables L27 domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MPP7-DLG1-LIN7 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein lin-7 homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      80319701..80471918 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001087299.4 → XP_001087299.1  protein lin-7 homolog A isoform X1

      See identical proteins and their annotated locations for XP_001087299.1

      UniProtKB/TrEMBL
      F7HGT6, H9FCG4
      Related
      ENSMMUP00000015316.4, ENSMMUT00000016346.4
      Conserved Domains (2) summary
      smart00569
      Location:31 → 83
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd00992
      Location:106 → 187
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    2. XM_028829755.1 → XP_028685588.1  protein lin-7 homolog A isoform X3

      Conserved Domains (1) summary
      cd00992
      Location:35 → 116
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    3. XM_028829754.1 → XP_028685587.1  protein lin-7 homolog A isoform X2

      UniProtKB/TrEMBL
      G7N7R4
      Conserved Domains (1) summary
      cd00992
      Location:40 → 121
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    RNA

    1. XR_001448120.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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