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    MGRN1 mahogunin ring finger 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709272, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MGRN1provided by VGNC
    Official Full Name
    mahogunin ring finger 1provided by VGNC
    Primary source
    VGNC:VGNC:74542
    See related
    Ensembl:ENSMMUG00000001888
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MGRN1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (4706313..4769775)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (4630077..4691968)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene chromosome 20 C16orf96 homolog Neighboring gene uncharacterized protein C8orf59 homolog Neighboring gene UBA like domain containing 1 Neighboring gene uncharacterized LOC114674291 Neighboring gene nudix hydrolase 16 like 1 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endosome to lysosome transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cAMP-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in early endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MGRN1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      4706313..4769775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015125543.2 → XP_014981029.1  E3 ubiquitin-protein ligase MGRN1 isoform X5

      UniProtKB/TrEMBL
      H9ERT4
      Conserved Domains (2) summary
      cd16789
      Location:278 → 318
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl29320
      Location:233 → 332
      KilA-N; KilA-N domain

    2. XM_015125539.2 → XP_014981025.1  E3 ubiquitin-protein ligase MGRN1 isoform X1

      UniProtKB/TrEMBL
      I0FGX4
      Conserved Domains (3) summary
      PHA03307
      Location:328 → 576
      PHA03307; transcriptional regulator ICP4; Provisional
      cd16789
      Location:278 → 318
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl29320
      Location:233 → 332
      KilA-N; KilA-N domain

    3. XM_015125545.2 → XP_014981031.1  E3 ubiquitin-protein ligase MGRN1 isoform X7

      UniProtKB/TrEMBL
      H9ERT4
      Conserved Domains (3) summary
      PHA02929
      Location:233 → 332
      PHA02929; N1R/p28-like protein; Provisional
      TIGR00599
      Location:274 → 505
      rad18; DNA repair protein rad18
      pfam13920
      Location:275 → 320
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

    4. XM_015125541.2 → XP_014981027.1  E3 ubiquitin-protein ligase MGRN1 isoform X3

      UniProtKB/TrEMBL
      H9Z6X6
      Conserved Domains (3) summary
      PHA03307
      Location:328 → 554
      PHA03307; transcriptional regulator ICP4; Provisional
      cd16789
      Location:278 → 318
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl29320
      Location:233 → 332
      KilA-N; KilA-N domain

    5. XM_015125544.2 → XP_014981030.1  E3 ubiquitin-protein ligase MGRN1 isoform X6

      UniProtKB/TrEMBL
      A0A5F7ZLW6, H9ERT4
      Related
      ENSMMUP00000066170.1, ENSMMUT00000090060.1
      Conserved Domains (2) summary
      cd16789
      Location:277 → 317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl29320
      Location:232 → 331
      KilA-N; KilA-N domain

    6. XM_015125540.2 → XP_014981026.1  E3 ubiquitin-protein ligase MGRN1 isoform X2

      UniProtKB/TrEMBL
      I0FGX4, I2CVL3
      Related
      ENSMMUP00000075650.1, ENSMMUT00000104164.1
      Conserved Domains (3) summary
      PHA03307
      Location:327 → 575
      PHA03307; transcriptional regulator ICP4; Provisional
      cd16789
      Location:277 → 317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl29320
      Location:232 → 331
      KilA-N; KilA-N domain

    7. XM_015125546.2 → XP_014981032.1  E3 ubiquitin-protein ligase MGRN1 isoform X8

      UniProtKB/TrEMBL
      H9ERT4
      Conserved Domains (3) summary
      TIGR00599
      Location:273 → 504
      rad18; DNA repair protein rad18
      cd16789
      Location:277 → 317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl29320
      Location:232 → 331
      KilA-N; KilA-N domain

    8. XM_015125542.2 → XP_014981028.1  E3 ubiquitin-protein ligase MGRN1 isoform X4

      UniProtKB/TrEMBL
      H9Z6X6, I2CWR2
      Related
      ENSMMUP00000080568.1, ENSMMUT00000102639.1
      Conserved Domains (3) summary
      PHA03307
      Location:327 → 553
      PHA03307; transcriptional regulator ICP4; Provisional
      cd16789
      Location:277 → 317
      mRING-HC-C3HC5_MGRN1_like---blasttree; Modified RING finger, HC subclass (C3HC5-type), found in mahogunin RING finger protein 1 (MGRN1), RING finger protein 157 (RNF157) and similar proteins
      cl29320
      Location:232 → 331
      KilA-N; KilA-N domain
    Nucleotide Protein
    Heading Accession and Version

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