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    PDIA3 protein disulfide isomerase family A member 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711029, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PDIA3provided by VGNC
    Official Full Name
    protein disulfide isomerase family A member 3provided by VGNC
    Primary source
    VGNC:VGNC:75905
    See related
    Ensembl:ENSMMUG00000001682
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    GRP58
    Orthologs
    human mouse all
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    Genomic context

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    See PDIA3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (20228526..20253916)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (20097251..20123167)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene stereocilin Neighboring gene cation channel sperm-associated protein 2-like Neighboring gene U6 spliceosomal RNA Neighboring gene elongation factor for RNA polymerase II 3 Neighboring gene small EDRK-rich factor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity. Pendyala G, et al. PLoS One, 2012. PMID 22715419, Free PMC Article
    2. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Magness CL, et al. Genome Biol, 2005. PMID 15998449, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The current study implicates PDIA3 to be an important cellular neuroprotective mechanism against a toxic drug
      Title: Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein disulfide isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to endoplasmic reticulum stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein disulfide-isomerase A3
    Names
    glucose regulated protein, 58kDa
    NP_001182645.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195716.1 → NP_001182645.1  protein disulfide-isomerase A3 precursor

      See identical proteins and their annotated locations for NP_001182645.1

      Status: VALIDATED

      Source sequence(s)
      CN647099, CN648700, CO648998
      UniProtKB/TrEMBL
      F6W4X0, F7G3A7, I0FG34
      Related
      ENSMMUP00000033720.2, ENSMMUT00000040684.3
      Conserved Domains (1) summary
      TIGR01130
      Location:25 → 487
      ER_PDI_fam; protein disulfide isomerase, eukaryotic

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      20228526..20253916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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