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    PLS3 plastin 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709055, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLS3provided by VGNC
    Official Full Name
    plastin 3provided by VGNC
    Primary source
    VGNC:VGNC:76181
    Locus tag
    EGK_20845
    See related
    Ensembl:ENSMMUG00000006377
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLS3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (112061983..112149815)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (109425365..109513632)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114669792 Neighboring gene small nucleolar RNA SNORA64/SNORA10 family Neighboring gene PHD finger-like domain-containing protein 5A pseudogene Neighboring gene argininosuccinate synthase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin filament bundle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plastin-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266221.1 → NP_001253150.1  plastin-3

      See identical proteins and their annotated locations for NP_001253150.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047397
      UniProtKB/TrEMBL
      A0A1D5QM74, A0A1D5RAY0, A0A8J8XHK4, F6WTT7, F7GYM9, G7NT69, H9ZA70
      Related
      ENSMMUP00000040861.3, ENSMMUT00000047833.3
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21328
      Location:254 → 375
      CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
      cd21331
      Location:377 → 510
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:519 → 630
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      112061983..112149815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127994.2 → XP_014983480.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      F7GYM9
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily

    2. XM_015127996.2 → XP_014983482.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      F7GYM9
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily

    3. XM_015127998.2 → XP_014983484.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      F7GYM9
      Related
      ENSMMUP00000008409.4, ENSMMUT00000008944.4
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily

    4. XM_028841800.1 → XP_028697633.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      F7GYM9
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily

    5. XM_015127995.1 → XP_014983481.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      F7GYM9
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily

    6. XM_015127999.1 → XP_014983485.1  plastin-3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QM74, A0A1D5RAY0, A0A8J8XHK4, F6WTT7, F7GYM9, G7NT69, H9ZA70
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21328
      Location:254 → 375
      CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
      cd21331
      Location:377 → 510
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:519 → 630
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

    7. XM_015127997.2 → XP_014983483.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      F7GYM9
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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