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    ARHGAP6 Rho GTPase activating protein 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709978, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGAP6provided by VGNC
    Official Full Name
    Rho GTPase activating protein 6provided by VGNC
    Primary source
    VGNC:VGNC:70009
    See related
    Ensembl:ENSMMUG00000003896
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (10745388..11292172, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (10238401..10788167, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene midline 1 Neighboring gene holocytochrome c synthase Neighboring gene aspartate aminotransferase, mitochondrial pseudogene Neighboring gene amelogenin X-linked Neighboring gene uncharacterized LOC106995154 Neighboring gene LIM domain kinase 2 pseudogene Neighboring gene MSL complex subunit 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phospholipase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      10745388..11292172 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001094565.3 → XP_001094565.2  rho GTPase-activating protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZWI7, F7H5F6
      Related
      ENSMMUP00000005194.3, ENSMMUT00000005518.4
      Conserved Domains (1) summary
      cd04376
      Location:402 → 608
      RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...

    2. XM_028841949.1 → XP_028697782.1  rho GTPase-activating protein 6 isoform X2

      Conserved Domains (1) summary
      cd04376
      Location:378 → 584
      RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...

    3. XM_015126934.2 → XP_014982420.2  rho GTPase-activating protein 6 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZWI7
      Related
      ENSMMUP00000069005.1, ENSMMUT00000092901.1
      Conserved Domains (1) summary
      cd04376
      Location:222 → 428
      RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
    Nucleotide Protein
    Heading Accession and Version

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