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    SESN3 sestrin 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699329, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SESN3provided by VGNC
    Official Full Name
    sestrin 3provided by VGNC
    Primary source
    VGNC:VGNC:77291
    See related
    Ensembl:ENSMMUG00000009394
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    sestrin-3
    Orthologs
    human mouse all
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    Genomic context

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    See SESN3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (88412433..88479921, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (87794970..87862083, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 8 Neighboring gene endonuclease domain containing 1 Neighboring gene uncharacterized LOC106993438 Neighboring gene family with sequence similarity 76 member B Neighboring gene centrosomal protein 57 Neighboring gene myotubularin related protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables L-leucine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on peroxide as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to L-leucine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to leucine starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of response to reactive oxygen species IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sestrin-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266247.1 → NP_001253176.1  sestrin-3

      See identical proteins and their annotated locations for NP_001253176.1

      Status: PROVISIONAL

      Source sequence(s)
      JU333046
      UniProtKB/TrEMBL
      F7HEU9, G7NBP4
      Related
      ENSMMUP00000012297.2, ENSMMUT00000013120.4
      Conserved Domains (1) summary
      pfam04636
      Location:39 → 490
      PA26; PA26 p53-induced protein (sestrin)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      88412433..88479921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115453.2 → XP_014970939.1  sestrin-3 isoform X1

      UniProtKB/TrEMBL
      G7NBP4
      Conserved Domains (1) summary
      pfam04636
      Location:115 → 566
      PA26; PA26 p53-induced protein (sestrin)

    2. XM_015115454.2 → XP_014970940.1  sestrin-3 isoform X2

      UniProtKB/TrEMBL
      G7NBP4
      Conserved Domains (1) summary
      pfam04636
      Location:1 → 412
      PA26; PA26 p53-induced protein (sestrin)

    3. XM_028832553.1 → XP_028688386.1  sestrin-3 isoform X2

      UniProtKB/TrEMBL
      G7NBP4
      Conserved Domains (1) summary
      pfam04636
      Location:1 → 412
      PA26; PA26 p53-induced protein (sestrin)
    Nucleotide Protein
    Heading Accession and Version

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