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    TGFB3 transforming growth factor beta 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703239, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TGFB3provided by VGNC
    Official Full Name
    transforming growth factor beta 3provided by VGNC
    Primary source
    VGNC:VGNC:78335
    Locus tag
    EGK_18402
    See related
    Ensembl:ENSMMUG00000012069
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TGFB3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (138081226..138106018, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (138392308..138417396, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene ergosterol biosynthesis 28 homolog Neighboring gene tubulin tyrosine ligase like 5 Neighboring gene calmodulin-A pseudogene Neighboring gene ubiquitin-conjugating enzyme E2 L3 pseudogene Neighboring gene intraflagellar transport 43 Neighboring gene G-patch domain containing 2 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables type II transforming growth factor beta receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables type III transforming growth factor beta receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transforming growth factor beta-3 proprotein
    Names
    transforming growth factor beta-3 preproprotein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257475.1 → NP_001244404.1  transforming growth factor beta-3 proprotein precursor

      See identical proteins and their annotated locations for NP_001244404.1

      Status: PROVISIONAL

      Source sequence(s)
      JU320356
      UniProtKB/TrEMBL
      A0A8J8XIW7, F7HDK4, G7MYV3
      Conserved Domains (2) summary
      cd19386
      Location:312 → 412
      TGF_beta_TGFB3; transforming growth factor beta (TGF-beta) like domain found in transforming growth factor beta-3 (TGF-beta-3) and similar proteins
      pfam00688
      Location:24 → 230
      TGFb_propeptide; TGF-beta propeptide

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      138081226..138106018 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144130.2 → XP_014999616.1  transforming growth factor beta-3 proprotein isoform X1

      UniProtKB/TrEMBL
      A0A8J8XIW7, F7HDK4, G7MYV3
      Related
      ENSMMUP00000015831.2, ENSMMUT00000016903.4
      Conserved Domains (2) summary
      cd19386
      Location:312 → 412
      TGF_beta_TGFB3; transforming growth factor beta (TGF-beta) like domain found in transforming growth factor beta-3 (TGF-beta-3) and similar proteins
      pfam00688
      Location:24 → 230
      TGFb_propeptide; TGF-beta propeptide

    2. XM_028850305.1 → XP_028706138.1  transforming growth factor beta-3 proprotein isoform X2

      Conserved Domains (1) summary
      pfam00019
      Location:68 → 166
      TGF_beta; Transforming growth factor beta like domain
    Nucleotide Protein
    Heading Accession and Version

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