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    MAMU-F major histocompatibility complex, class I, F [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709076, updated on 9-Nov-2023

    Summary

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    Gene symbol
    MAMU-F
    Gene description
    major histocompatibility complex, class I, F
    See related
    Ensembl:ENSMMUG00000008799
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    HLAF; Mamu-A
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See MAMU-F in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (140510624..140513214, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (30176724..30179314)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC719778 Neighboring gene HLA class I histocompatibility antigen, B-38 alpha chain-like Neighboring gene uncharacterized LOC106997874 Neighboring gene ZFP57 zinc finger protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the rhesus macaque (Macaca mulatta) equivalent of HLA-F. Otting N, et al. Immunogenetics, 1993. PMID 8482576
    2. Genomic evolution of MHC class I region in primates. Fukami-Kobayashi K, et al. Proc Natl Acad Sci U S A, 2005 Jun 28. PMID 15967992, Free PMC Article
    3. Rhesus macaque class I duplicon structures, organization, and evolution within the alpha block of the major histocompatibility complex. Kulski JK, et al. Mol Biol Evol, 2004 Nov. PMID 15269276
    4. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. Shiina T, et al. Genetics, 2006 Jul. PMID 16702430, Free PMC Article
    5. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables peptide antigen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antigen processing and presentation of endogenous peptide antigen via MHC class Ib IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mamu class I histocompatibility antigen, alpha chain F
    Names
    HLA F antigen
    HLA class I histocompatibility antigen, alpha chain F
    MHC class I antigen F
    MHC class I protein
    leukocyte antigen F

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042770.2 → NP_001036235.2  mamu class I histocompatibility antigen, alpha chain F precursor

      See identical proteins and their annotated locations for NP_001036235.2

      Status: PROVISIONAL

      Source sequence(s)
      Z21819
      UniProtKB/Swiss-Prot
      P33617
      UniProtKB/TrEMBL
      A0A238U3L5, A0A238U3L6, A0A238U3M5, A0A238U3U7, A0A238U5A7, A0A238U5P0, A3F8Y0, D7RD86
      Related
      ENSMMUP00000011541.3, ENSMMUT00000012303.4
      Conserved Domains (2) summary
      cd07698
      Location:206 → 298
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:22 → 202
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      140510624..140513214 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P33617.2 GenPept UniProtKB/Swiss-Prot:P33617

    Gene LinkOut

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    Research Materials