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    NKX2-1 NK2 homeobox 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696771, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NKX2-1provided by VGNC
    Official Full Name
    NK2 homeobox 1provided by VGNC
    Primary source
    VGNC:VGNC:84409
    See related
    Ensembl:ENSMMUG00000009641
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    TITF1
    Orthologs
    human mouse all
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    Genomic context

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    See NKX2-1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (98588854..98595003, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (97928087..97933931, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999401 Neighboring gene U7 small nuclear RNA Neighboring gene surfactant associated 3 Neighboring gene 60S ribosomal protein L29-like Neighboring gene NK2 homeobox 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein Nkx-2.1
    Names
    homeobox protein Nkx-2.1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      98588854..98595003 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015143586.2 → XP_014999072.1  homeobox protein Nkx-2.1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8ASM6
      Conserved Domains (1) summary
      pfam00046
      Location:164 → 218
      Homeobox; Homeobox domain

    2. XM_028851499.1 → XP_028707332.1  homeobox protein Nkx-2.1 isoform X1

      UniProtKB/TrEMBL
      F6YQK0
      Conserved Domains (1) summary
      pfam00046
      Location:194 → 248
      Homeobox; Homeobox domain

    3. XM_028851500.1 → XP_028707333.1  homeobox protein Nkx-2.1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8ASM6
      Related
      ENSMMUP00000080082.1, ENSMMUT00000108788.1
      Conserved Domains (1) summary
      pfam00046
      Location:164 → 218
      Homeobox; Homeobox domain

    4. XM_001089773.3 → XP_001089773.1  homeobox protein Nkx-2.1 isoform X1

      See identical proteins and their annotated locations for XP_001089773.1

      UniProtKB/TrEMBL
      F6YQK0
      Related
      ENSMMUP00000012615.3, ENSMMUT00000013463.3
      Conserved Domains (1) summary
      pfam00046
      Location:194 → 248
      Homeobox; Homeobox domain

    5. XM_015143584.2 → XP_014999070.1  homeobox protein Nkx-2.1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8ASM6
      Conserved Domains (1) summary
      pfam00046
      Location:164 → 218
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version

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