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    MTHFS methenyltetrahydrofolate synthetase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717493, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MTHFSprovided by VGNC
    Official Full Name
    methenyltetrahydrofolate synthetaseprovided by VGNC
    Primary source
    VGNC:VGNC:84401
    Locus tag
    EGK_17741
    See related
    Ensembl:ENSMMUG00000015224
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MTHFS in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (57142008..57192712, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (57371984..57422646, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114679468 Neighboring gene basic salivary proline-rich protein 2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5-formyltetrahydrofolate cyclo-ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in folic acid-containing compound biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tetrahydrofolate interconversion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5-formyltetrahydrofolate cyclo-ligase
    Names
    5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
    NP_001253007.1
    XP_028706383.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266078.1 → NP_001253007.1  5-formyltetrahydrofolate cyclo-ligase

      See identical proteins and their annotated locations for NP_001253007.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045948
      UniProtKB/TrEMBL
      A0A1D5QRQ4, A0A8J8XM46, F6VVW7, G7MYH0
      Related
      ENSMMUP00000050732.2, ENSMMUT00000075729.2
      Conserved Domains (1) summary
      pfam01812
      Location:10 → 198
      5-FTHF_cyc-lig; 5-formyltetrahydrofolate cyclo-ligase family

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      57142008..57192712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028850550.1 → XP_028706383.1  5-formyltetrahydrofolate cyclo-ligase isoform X1

      Conserved Domains (1) summary
      pfam01812
      Location:1 → 141
      5-FTHF_cyc-lig; 5-formyltetrahydrofolate cyclo-ligase family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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