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    CDK8 cyclin dependent kinase 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709761, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CDK8provided by VGNC
    Official Full Name
    cyclin dependent kinase 8provided by VGNC
    Primary source
    VGNC:VGNC:70984
    See related
    Ensembl:ENSMMUG00000014841
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CDK8 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (5607477..5756968)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (5837840..5987872)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene 52 kDa repressor of the inhibitor of the protein kinase-like Neighboring gene ring finger protein 6 Neighboring gene neuronal regeneration-related protein pseudogene Neighboring gene uncharacterized LOC114673455 Neighboring gene 40S ribosomal protein S3a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 8
    NP_001248269.1
    XP_014976200.1
    XP_014976201.1
    XP_014976202.1
    XP_028692977.1
    XP_028692978.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261340.1 → NP_001248269.1  cyclin-dependent kinase 8

      See identical proteins and their annotated locations for NP_001248269.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045870
      UniProtKB/TrEMBL
      A0A1D5QPF2, F6VP38, H9FNK1
      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      5607477..5756968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015120714.2 → XP_014976200.1  cyclin-dependent kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QPF2
      Related
      ENSMMUP00000049929.2, ENSMMUT00000066146.2
      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    2. XM_028837144.1 → XP_028692977.1  cyclin-dependent kinase 8 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 162
      PKc_like; Protein Kinases, catalytic domain

    3. XM_015120715.1 → XP_014976201.1  cyclin-dependent kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QPF2
      Conserved Domains (1) summary
      cl21453
      Location:3 → 287
      PKc_like; Protein Kinases, catalytic domain

    4. XM_015120716.2 → XP_014976202.1  cyclin-dependent kinase 8 isoform X3

      UniProtKB/TrEMBL
      G7NJT5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 275
      PKc_like; Protein Kinases, catalytic domain

    5. XM_028837145.1 → XP_028692978.1  cyclin-dependent kinase 8 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 162
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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