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    ZSWIM2 zinc finger SWIM-type containing 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707980, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ZSWIM2provided by VGNC
    Official Full Name
    zinc finger SWIM-type containing 2provided by VGNC
    Primary source
    VGNC:VGNC:79908
    See related
    Ensembl:ENSMMUG00000004022
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ZSWIM2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (73941836..73963083, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (74128860..74150380, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106992659 Neighboring gene integrin subunit alpha V Neighboring gene family with sequence similarity 171 member B Neighboring gene inosine-5'-monophosphate dehydrogenase 1 pseudogene Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase ZSWIM2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      73941836..73963083 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001104099.4 → XP_001104099.3  E3 ubiquitin-protein ligase ZSWIM2

      UniProtKB/TrEMBL
      F6XH39
      Related
      ENSMMUP00000005365.3, ENSMMUT00000005699.3
      Conserved Domains (4) summary
      COG5540
      Location:280 → 384
      COG5540; RING-finger-containing ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      cl00295
      Location:232 → 275
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
      cd16486
      Location:343 → 386
      mRING-H2-C3H2C2D_ZSWM2; Modified RING finger, H2 subclass (C3H2C2D-type), found in zinc finger SWIM domain-containing protein 2 (ZSWIM2) and similar proteins
      cd16494
      Location:144 → 201
      RING-CH-C4HC3_ZSWM2; RING-CH finger, H2 subclass (C4HC3-type), found in zinc finger SWIM domain-containing protein 2 (ZSWIM2) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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