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    SPPL2C signal peptide peptidase like 2C [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717107, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPPL2Cprovided by VGNC
    Official Full Name
    signal peptide peptidase like 2Cprovided by VGNC
    Primary source
    VGNC:VGNC:104659
    See related
    Ensembl:ENSMMUG00000061173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPPL2C in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (57642965..57645194)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (52298468..52301805)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene corticotropin releasing hormone receptor 1 Neighboring gene uncharacterized LOC114673218 Neighboring gene uncharacterized LOC106994068 Neighboring gene microtubule associated protein tau Neighboring gene saitohin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane protein proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi-associated vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasmic side of endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lumenal side of endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal peptide peptidase-like 2C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      57642965..57645194
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001115879.4 → XP_001115879.2  signal peptide peptidase-like 2C

      UniProtKB/TrEMBL
      A0A5F7ZA39, G7NJ61
      Related
      ENSMMUP00000062425.1, ENSMMUT00000091068.1
      Conserved Domains (2) summary
      cl28883
      Location:38 → 175
      PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...
      cl01342
      Location:245 → 529
      Peptidase_A22B; Signal peptide peptidase
    Nucleotide Protein
    Heading Accession and Version

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