U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GAD2 glutamate decarboxylase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 613029, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GAD2provided by VGNC
    Official Full Name
    glutamate decarboxylase 2provided by VGNC
    Primary source
    VGNC:VGNC:72863
    Locus tag
    EGK_19532
    See related
    Ensembl:ENSMMUG00000012233
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    GAD65
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GAD2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (27214469..27303983)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (26328754..26418355)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene myosin IIIA Neighboring gene uncharacterized LOC107000077 Neighboring gene amyloid beta precursor protein binding family B member 1 interacting protein Neighboring gene uncharacterized LOC114669908

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Glutamic acid decarboxylase isoform 65 immunoreactivity in the motor thalamus of humans and monkeys: γ-aminobutyric acidergic connections and nuclear delineations. Kultas-Ilinsky K, et al. J Comp Neurol, 2011 Oct 1. PMID 21491431
    2. Role of glutamic acid decarboxylase in the prepubertal inhibition of the luteinizing hormone releasing hormone release in female rhesus monkeys. Mitsushima D, et al. J Neurosci, 1996 Apr 15. PMID 8786432, Free PMC Article
    3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    4. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results describe the gross distribution patterns of GAD65 in human and rhesus monkey thalami and show that they are nearly identical.
      Title: Glutamic acid decarboxylase isoform 65 immunoreactivity in the motor thalamus of humans and monkeys: γ-aminobutyric acidergic connections and nuclear delineations.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutamate decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gamma-aminobutyrate shunt IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    glutamate decarboxylase 2
    Names
    glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    glutamic acid decarboxylase
    NP_001252783.1
    XP_015002128.2
    XP_028709060.1
    XP_028709062.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265854.1 → NP_001252783.1  glutamate decarboxylase 2

      See identical proteins and their annotated locations for NP_001252783.1

      Status: PROVISIONAL

      Source sequence(s)
      JU333831
      UniProtKB/TrEMBL
      A0A8J8XZF1, F6VEZ9, G7N1R9, H9FSH7
      Related
      ENSMMUP00000045318.2, ENSMMUT00000072190.2
      Conserved Domains (1) summary
      pfam00282
      Location:138 → 509
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      27214469..27303983
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015146642.2 → XP_015002128.2  glutamate decarboxylase 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QBA0, A0A1D5QVP7, F6VEZ9
      Conserved Domains (1) summary
      pfam00282
      Location:138 → 509
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

    2. XM_028853227.1 → XP_028709060.1  glutamate decarboxylase 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QBA0, A0A1D5QVP7, F6VEZ9
      Related
      ENSMMUP00000052127.2, ENSMMUT00000055410.2
      Conserved Domains (1) summary
      pfam00282
      Location:138 → 509
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

    3. XM_028853229.1 → XP_028709062.1  glutamate decarboxylase 2 isoform X2

      UniProtKB/TrEMBL
      F6VEZ9
      Conserved Domains (1) summary
      pfam00282
      Location:88 → 459
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials