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    MKI67 marker of proliferation Ki-67 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697883, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MKI67provided by VGNC
    Official Full Name
    marker of proliferation Ki-67provided by VGNC
    Primary source
    VGNC:VGNC:106075
    See related
    Ensembl:ENSMMUG00000044121
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    Ki-67
    Orthologs
    human mouse all
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    Genomic context

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    See MKI67 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (128522685..128554144, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (124207527..124238885, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene clarin 3 Neighboring gene protein tyrosine phosphatase receptor type E Neighboring gene uncharacterized LOC114670069 Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mitotic nuclear division IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    antigen KI-67; proliferation marker protein Ki-67
    Names
    antigen identified by monoclonal antibody Ki-67
    antigen of monoclonal antibody Ki-67

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      128522685..128554144 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148453.2 → XP_015003939.2  proliferation marker protein Ki-67 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RER2, G7N1E1
      Related
      ENSMMUP00000058805.2, ENSMMUT00000060885.2
      Conserved Domains (3) summary
      pfam08065
      Location:1367 → 1474
      K167R; K167R (NUC007) repeat
      pfam15276
      Location:502 → 556
      PP1_bind; Protein phosphatase 1 binding
      pfam00498
      Location:27 → 90
      FHA; FHA domain

    2. XM_015148454.2 → XP_015003940.2  proliferation marker protein Ki-67 isoform X3

      UniProtKB/TrEMBL
      G7N1E1
      Conserved Domains (3) summary
      pfam08065
      Location:1008 → 1115
      K167R; K167R (NUC007) repeat
      pfam15276
      Location:143 → 197
      PP1_bind; Protein phosphatase 1 binding
      pfam00498
      Location:27 → 90
      FHA; FHA domain

    3. XM_028827007.1 → XP_028682840.1  proliferation marker protein Ki-67 isoform X2

      UniProtKB/TrEMBL
      G7N1E1
      Conserved Domains (2) summary
      pfam08065
      Location:1125 → 1232
      K167R; K167R (NUC007) repeat
      pfam15276
      Location:260 → 314
      PP1_bind; Protein phosphatase 1 binding
    Nucleotide Protein
    Heading Accession and Version

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