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    DTL denticleless E3 ubiquitin protein ligase homolog [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711236, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DTLprovided by VGNC
    Official Full Name
    denticleless E3 ubiquitin protein ligase homologprovided by VGNC
    Primary source
    VGNC:VGNC:71992
    Locus tag
    EGK_01678
    See related
    Ensembl:ENSMMUG00000010176
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DTL in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (69530274..69598632)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (154414246..154490944, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 pseudogene Neighboring gene integrator complex subunit 7 Neighboring gene small nucleolar RNA SNORA26 Neighboring gene microRNA mir-3122 Neighboring gene uncharacterized LOC114680353 Neighboring gene uncharacterized LOC106993689

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-macromolecule adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic G2 DNA damage checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    denticleless protein homolog
    Names
    denticleless homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260630.1 → NP_001247559.1  denticleless protein homolog

      See identical proteins and their annotated locations for NP_001247559.1

      Status: PROVISIONAL

      Source sequence(s)
      JU475917
      UniProtKB/TrEMBL
      A0A8J8YHN9, F6SRE7, G7MEM1, H9Z9V5
      Related
      ENSMMUP00000013304.3, ENSMMUT00000014206.3
      Conserved Domains (3) summary
      COG2319
      Location:37 → 410
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:55 → 389
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:55 → 96
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      69530274..69598632
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015116745.2 → XP_014972231.2  denticleless protein homolog isoform X1

      UniProtKB/TrEMBL
      F6SRD8
      Conserved Domains (2) summary
      cd00200
      Location:3 → 327
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:39 → 75
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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