These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001257456.1 → NP_001244385.1  histone-lysine N-methyltransferase EZH1

   See identical proteins and their annotated locations for NP_001244385.1

   Status: PROVISIONAL

   Source sequence(s)

   JU320536

   UniProtKB/TrEMBL

   F7B7S5, G7NIM5, H9EPI3

   Related

   ENSMMUP00000008007.4, ENSMMUT00000008519.4

   Conserved Domains (5) summary

   COG2940
   Location:463 → 727

   SET; SET domain-containing protein (function unknown) [General function prediction only]

   cd00167
   Location:433 → 474

   SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

   cd19217
   Location:608 → 743

   SET_EZH1; SET domain found in enhancer of zeste homolog 1 (EZH1) and similar proteins

   pfam11616
   Location:39 → 68

   EZH2_WD-Binding; WD repeat binding protein EZH2

   pfam18118
   Location:159 → 262

   PRC2_HTH_1; Polycomb repressive complex 2 tri-helical domain

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference Mmul_10 Primary Assembly

Genomic

1. NC_041769.1 Reference Mmul_10 Primary Assembly

   Range

   53832416..53877884 complement

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_028835577.1 → XP_028691410.1  histone-lysine N-methyltransferase EZH1 isoform X3

   Conserved Domains (3) summary

   smart00317
   Location:474 → 595

   SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain

   COG2940
   Location:324 → 588

   SET; SET domain-containing protein (function unknown) [General function prediction only]

   cd00167
   Location:294 → 335

   SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

2. XM_015119723.2 → XP_014975209.1  histone-lysine N-methyltransferase EZH1 isoform X1

   UniProtKB/TrEMBL

   G7NIM5

   Conserved Domains (5) summary

   COG2940
   Location:454 → 718

   SET; SET domain-containing protein (function unknown) [General function prediction only]

   cd00167
   Location:424 → 465

   SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

   pfam11616
   Location:39 → 67

   EZH2_WD-Binding; WD repeat binding protein EZH2

   pfam18118
   Location:150 → 253

   PRC2_HTH_1; Polycomb repressive complex 2 tri-helical domain

   cd19217
   Location:599 → 734

   SET_EZH1; SET domain found in enhancer of zeste homolog 1 (EZH1) and similar proteins

3. XM_015119724.2 → XP_014975210.1  histone-lysine N-methyltransferase EZH1 isoform X2

   UniProtKB/TrEMBL

   G7NIM5

   Conserved Domains (5) summary

   COG2940
   Location:423 → 687

   SET; SET domain-containing protein (function unknown) [General function prediction only]

   cd00167
   Location:393 → 434

   SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

   cd19217
   Location:568 → 703

   SET_EZH1; SET domain found in enhancer of zeste homolog 1 (EZH1) and similar proteins

   pfam11616
   Location:39 → 68

   EZH2_WD-Binding; WD repeat binding protein EZH2

   pfam18118
   Location:119 → 222

   PRC2_HTH_1; Polycomb repressive complex 2 tri-helical domain