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    ASB6 ankyrin repeat and SOCS box containing 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716732, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ASB6provided by VGNC
    Official Full Name
    ankyrin repeat and SOCS box containing 6provided by VGNC
    Primary source
    VGNC:VGNC:69850
    Locus tag
    EGK_07288
    See related
    Ensembl:ENSMMUG00000011816
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ASB6 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (10886531..10894341)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (9076585..9084096)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene prostaglandin E synthase Neighboring gene paired related homeobox 2 Neighboring gene uncharacterized LOC114672714 Neighboring gene chromosome 15 C9orf50 homolog Neighboring gene N-terminal Xaa-Pro-Lys N-methyltransferase 1 Neighboring gene uncharacterized LOC106993593 Neighboring gene uncharacterized LOC114672716

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of BRCA1-BARD1 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      10886531..10894341
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015116636.2 → XP_014972122.1  ankyrin repeat and SOCS box protein 6 isoform X2

      UniProtKB/TrEMBL
      F7H7C0
      Related
      ENSMMUP00000015502.3, ENSMMUT00000016551.4
      Conserved Domains (4) summary
      cd00204
      Location:25 → 135
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd03725
      Location:291 → 334
      SOCS_ASB6; SOCS (suppressors of cytokine signaling) box of ASB6-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB6 interacts with the adaptor protein APS and recruits elongin B/C to the insulin receptor ...
      pfam12796
      Location:28 → 127
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:26 → 54
      ANK; ANK repeat [structural motif]

    2. XM_001107816.4 → XP_001107816.1  ankyrin repeat and SOCS box protein 6 isoform X1

      See identical proteins and their annotated locations for XP_001107816.1

      UniProtKB/TrEMBL
      A0A5F7Z712, A0A8J8XWC7, G7NFK1, H9ERC4
      Related
      ENSMMUP00000061178.1, ENSMMUT00000093858.1
      Conserved Domains (4) summary
      PHA02884
      Location:7 → 130
      PHA02884; ankyrin repeat protein; Provisional
      PHA03095
      Location:88 → 284
      PHA03095; ankyrin-like protein; Provisional
      cd03725
      Location:370 → 413
      SOCS_ASB6; SOCS (suppressors of cytokine signaling) box of ASB6-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB6 interacts with the adaptor protein APS and recruits elongin B/C to the insulin receptor ...
      sd00045
      Location:105 → 133
      ANK; ANK repeat [structural motif]

    3. XM_015116637.2 → XP_014972123.1  ankyrin repeat and SOCS box protein 6 isoform X3

      Conserved Domains (3) summary
      cd00204
      Location:41 → 135
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:41 → 133
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:67 → 99
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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