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    UBR1 ubiquitin protein ligase E3 component n-recognin 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709238, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UBR1provided by VGNC
    Official Full Name
    ubiquitin protein ligase E3 component n-recognin 1provided by VGNC
    Primary source
    VGNC:VGNC:79051
    Locus tag
    EGK_17415
    See related
    Ensembl:ENSMMUG00000006498
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See UBR1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (19452270..19612299, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (19377301..19535107, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene tau tubulin kinase 2 Neighboring gene keratin, type II cytoskeletal 8 pseudogene Neighboring gene farnesyl pyrophosphate synthase pseudogene Neighboring gene farnesyl pyrophosphate synthase pseudogene Neighboring gene signal peptidase complex subunit 2-like Neighboring gene transmembrane protein 62

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase UBR1
    XP_014997532.1
    XP_014997533.1
    XP_028706627.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      19452270..19612299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015142046.2 → XP_014997532.1  E3 ubiquitin-protein ligase UBR1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QDD6, A0A663DG36, A0A8J8XQB9, F7H925, G7MWZ8, H9EQU7
      Related
      ENSMMUP00000046055.2, ENSMMUT00000062614.2
      Conserved Domains (2) summary
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:221 → 301
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    2. XM_015142047.2 → XP_014997533.1  E3 ubiquitin-protein ligase UBR1 isoform X3

      UniProtKB/TrEMBL
      F7H916
      Conserved Domains (2) summary
      pfam02207
      Location:2 → 42
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:97 → 177
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    3. XM_028850794.1 → XP_028706627.1  E3 ubiquitin-protein ligase UBR1 isoform X2

      UniProtKB/TrEMBL
      F7H916
      Related
      ENSMMUP00000008564.3, ENSMMUT00000009115.4
      Conserved Domains (3) summary
      cd16685
      Location:1040 → 1158
      RING-H2_UBR1; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-1 (UBR1) and similar proteins
      pfam02207
      Location:45 → 112
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:167 → 247
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    RNA

    1. XR_001445858.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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