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    NECTIN2 nectin cell adhesion molecule 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713229, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NECTIN2provided by VGNC
    Official Full Name
    nectin cell adhesion molecule 2provided by VGNC
    Primary source
    VGNC:VGNC:75396
    See related
    Ensembl:ENSMMUG00000014301
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NECTIN2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (44884662..44928306)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (40154130..40187427)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene Cbl proto-oncogene C Neighboring gene basal cell adhesion molecule Neighboring gene translocase of outer mitochondrial membrane 40 Neighboring gene apolipoprotein E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acrosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in coreceptor-mediated virion attachment to host cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of mitochondrion localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fusion of virus membrane with host plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of immunoglobulin mediated immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of mast cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of viral entry into host cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in susceptibility to T cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in susceptibility to natural killer cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical junction complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular exosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nectin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001043593.1 → NP_001037058.1  nectin-2 precursor

      See identical proteins and their annotated locations for NP_001037058.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ851093
      UniProtKB/TrEMBL
      A0A5F7ZG31, Q0MSE5
      Related
      ENSMMUP00000064583.1, ENSMMUT00000102795.1
      Conserved Domains (3) summary
      smart00410
      Location:40 → 158
      IG_like; Immunoglobulin like
      pfam13927
      Location:280 → 333
      Ig_3; Immunoglobulin domain
      cl11960
      Location:162 → 257
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      44884662..44928306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838459.1 → XP_028694292.1  nectin-2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R5U5, F7BSK9, I0FI24
      Related
      ENSMMUP00000018783.4, ENSMMUT00000020068.4
      Conserved Domains (2) summary
      pfam13927
      Location:260 → 333
      Ig_3; Immunoglobulin domain
      cl11960
      Location:162 → 257
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.