SELENOT selenoprotein T [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: SELENOTprovided by VGNC
Official Full Name: selenoprotein Tprovided by VGNC
Primary source: VGNC:VGNC:84084
See related: Ensembl:ENSMMUG00000017699
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: SELT
Summary: This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. [provided by RefSeq, Jul 2017]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	2	NC_041755.1 (52741582..52775090)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	2	NC_027894.1 (137360168..137393594)

Chromosome 2 - NC_041755.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-59809 (e-PCR)
- UniSTS:76305

G44299 (e-PCR)
- UniSTS:95093

RH65015 (e-PCR)
- UniSTS:85625

G19688 (e-PCR)
- UniSTS:17312

RH80692 (e-PCR)
- UniSTS:85664

A001V27 (e-PCR)
- UniSTS:17313

D10S1175 (e-PCR)
- UniSTS:149417

GDB:451721 (e-PCR)
- UniSTS:157354

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables thioredoxin-disulfide reductase (NADPH) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell redox homeostasis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: thioredoxin reductase-like selenoprotein T

NP_001152886.1

EC 1.8.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.