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    ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713575, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITIH2provided by VGNC
    Official Full Name
    inter-alpha-trypsin inhibitor heavy chain 2provided by VGNC
    Primary source
    VGNC:VGNC:73794
    See related
    Ensembl:ENSMMUG00000015954
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITIH2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (8799419..8845479)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (7656586..7702518)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene inter-alpha-trypsin inhibitor heavy chain 5 Neighboring gene Kin17 DNA and RNA binding protein Neighboring gene ATP synthase F1 subunit gamma

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hyaluronan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inter-alpha-trypsin inhibitor heavy chain H2
    Names
    inter-alpha (globulin) inhibitor H2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      8799419..8845479
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001107718.3 → XP_001107718.2  inter-alpha-trypsin inhibitor heavy chain H2

      UniProtKB/TrEMBL
      F7DD08, G7N1J8
      Related
      ENSMMUP00000020989.4, ENSMMUT00000022435.4
      Conserved Domains (3) summary
      smart00609
      Location:56 → 185
      VIT; Vault protein Inter-alpha-Trypsin domain
      cd01461
      Location:307 → 488
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      pfam06668
      Location:735 → 921
      ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus
    Nucleotide Protein
    Heading Accession and Version

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