XCL1 chemokine (C motif) ligand 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: XCL1
Gene description: chemokine (C motif) ligand 1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	1	NC_041754.1 (25890736..25893721, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	1	NC_027893.1 (199103396..199273432, complement)

Chromosome 1 - NC_041754.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH91674 (e-PCR)
- UniSTS:86631

NoName (e-PCR)
- UniSTS:481472

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CCR chemokine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to interleukin-1	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to tumor necrosis factor	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to type II interferon	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lymphocyte chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in monocyte chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neutrophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of ERK1 and ERK2 cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: lymphotactin

Names: X-C motif chemokine ligand 1; chemokine XCL1/LYMPHOTACTIN

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001032947.1 → NP_001028119.1 lymphotactin precursor

See identical proteins and their annotated locations for NP_001028119.1

Status: PROVISIONAL

Source sequence(s)

AF449285

UniProtKB/TrEMBL

Q8HXZ2

Conserved Domains (1) summary

cd00271
Location:22 → 93

Chemokine_C; Chemokine_C, C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273) ...