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    PGRMC2 progesterone receptor membrane component 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693565, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PGRMC2provided by VGNC
    Official Full Name
    progesterone receptor membrane component 2provided by VGNC
    Primary source
    VGNC:VGNC:107190
    See related
    Ensembl:ENSMMUG00000056828
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PGRMC2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (126049769..126070704, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (127600014..127619877, complement)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene La ribonucleoprotein 1B Neighboring gene fos-related antigen 1 pseudogene Neighboring gene uncharacterized LOC114678394 Neighboring gene uncharacterized LOC114678395 Neighboring gene uncharacterized LOC106998496 Neighboring gene uncharacterized LOC114678396

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alterations in progesterone receptor membrane component 2 (PGRMC2) in the endometrium of macaques afflicted with advanced endometriosis. Keator CS, et al. Mol Hum Reprod, 2012 Jun. PMID 22307145, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that reduced levels of membrane-bound PGRMC2 are associated with progesterone insensitivity observed in endometrium in a primate model of endometriosis.
      Title: Alterations in progesterone receptor membrane component 2 (PGRMC2) in the endometrium of macaques afflicted with advanced endometriosis.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    membrane-associated progesterone receptor component 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      126049769..126070704 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001082791.4 → XP_001082791.1  membrane-associated progesterone receptor component 2

      Related
      ENSMMUP00000071624.1, ENSMMUT00000105861.1
      Conserved Domains (1) summary
      pfam00173
      Location:126 → 224
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    Nucleotide Protein
    Heading Accession and Version

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