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    STAT5B signal transducer and activator of transcription 5B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709760, updated on 17-Aug-2024

    Summary

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    Official Symbol
    STAT5Bprovided by VGNC
    Official Full Name
    signal transducer and activator of transcription 5Bprovided by VGNC
    Primary source
    VGNC:VGNC:99275
    See related
    Ensembl:ENSMMUG00000003437
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See STAT5B in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (53322391..53413152, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (48060541..48126456, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene hypocretin neuropeptide precursor Neighboring gene GH3 domain containing Neighboring gene signal transducer and activator of transcription 5A Neighboring gene signal transducer and activator of transcription 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal transducer and activator of transcription 5B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      53322391..53413152 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028836505.1 → XP_028692338.1  signal transducer and activator of transcription 5B isoform X1

      UniProtKB/TrEMBL
      F7F598, H9FYY3, H9FYY5
      Conserved Domains (4) summary
      cd10420
      Location:573 → 717
      SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
      cd16855
      Location:139 → 330
      STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      cd16849
      Location:332 → 489
      STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      pfam02865
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain

    2. XM_028836506.1 → XP_028692339.1  signal transducer and activator of transcription 5B isoform X1

      UniProtKB/TrEMBL
      F7F598, H9FYY3, H9FYY5
      Related
      ENSMMUP00000058264.2, ENSMMUT00000075321.2
      Conserved Domains (4) summary
      cd10420
      Location:573 → 717
      SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
      cd16855
      Location:139 → 330
      STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      cd16849
      Location:332 → 489
      STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      pfam02865
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain

    3. XM_028836504.1 → XP_028692337.1  signal transducer and activator of transcription 5B isoform X1

      UniProtKB/TrEMBL
      F7F598, H9FYY3, H9FYY5
      Related
      ENSMMUP00000004582.4, ENSMMUT00000004862.4
      Conserved Domains (4) summary
      cd10420
      Location:573 → 717
      SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
      cd16855
      Location:139 → 330
      STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      cd16849
      Location:332 → 489
      STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      pfam02865
      Location:2 → 124
      STAT_int; STAT protein, protein interaction domain

    4. XM_028836507.1 → XP_028692340.1  signal transducer and activator of transcription 5B isoform X2

      UniProtKB/TrEMBL
      H9ZCU3
      Conserved Domains (4) summary
      cd10420
      Location:471 → 615
      SH2_STAT5b; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins
      cd16855
      Location:37 → 228
      STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      cd16849
      Location:230 → 387
      STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
      cl03749
      Location:1 → 22
      STAT_int; STAT protein, protein interaction domain
    Nucleotide Protein
    Heading Accession and Version

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