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    PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713854, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PCBD2provided by VGNC
    Official Full Name
    pterin-4 alpha-carbinolamine dehydratase 2provided by VGNC
    Primary source
    VGNC:VGNC:75672
    See related
    Ensembl:ENSMMUG00000058022
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PCBD2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (132366447..132415502)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (132623850..132672700)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene chromosome 6 C5orf24 homolog Neighboring gene thioredoxin domain containing 15 Neighboring gene cation channel sperm associated 3 Neighboring gene paired like homeodomain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4-alpha-hydroxytetrahydrobiopterin dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tetrahydrobiopterin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pterin-4-alpha-carbinolamine dehydratase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      132366447..132415502
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849735.1 → XP_028705568.1  pterin-4-alpha-carbinolamine dehydratase 2 isoform X2

    2. XM_028849734.1 → XP_028705567.1  pterin-4-alpha-carbinolamine dehydratase 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8ATN2
      Related
      ENSMMUP00000081187.1, ENSMMUT00000110212.1
      Conserved Domains (1) summary
      cd00914
      Location:51 → 126
      PCD_DCoH_subfamily_b; PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by ...
    Nucleotide Protein
    Heading Accession and Version

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