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    ICA1 islet cell autoantigen 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695889, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ICA1provided by VGNC
    Official Full Name
    islet cell autoantigen 1provided by VGNC
    Primary source
    VGNC:VGNC:73551
    See related
    Ensembl:ENSMMUG00000005435
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ICA1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (106982509..107137892)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (100443508..100600411)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene LYR motif-containing protein 9-like Neighboring gene neurexophilin 1 Neighboring gene basic proline-rich protein Neighboring gene glucocorticoid induced 1 Neighboring gene peptidyl-prolyl cis-trans isomerase-like 4 Neighboring gene uncharacterized LOC106997528

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    islet cell autoantigen 1
    Names
    islet cell autoantigen 1, 69kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265706.2 → NP_001252635.1  islet cell autoantigen 1

      See identical proteins and their annotated locations for NP_001252635.1

      Status: PROVISIONAL

      Source sequence(s)
      JV565109
      UniProtKB/TrEMBL
      F7GQ13, I2CU09
      Related
      ENSMMUP00000007191.4, ENSMMUT00000007656.4
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 484
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      106982509..107137892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015133994.2 → XP_014989480.1  islet cell autoantigen 1 isoform X2

      UniProtKB/TrEMBL
      F7GQ13
      Conserved Domains (2) summary
      cd07661
      Location:52 → 255
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:261 → 483
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    2. XM_015133991.2 → XP_014989477.1  islet cell autoantigen 1 isoform X1

      UniProtKB/TrEMBL
      F7GQ13, I2CU09
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 484
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    3. XM_015133988.2 → XP_014989474.1  islet cell autoantigen 1 isoform X1

      UniProtKB/TrEMBL
      F7GQ13, I2CU09
      Related
      ENSMMUP00000076403.1, ENSMMUT00000093384.1
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 484
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    4. XM_015133997.2 → XP_014989483.1  islet cell autoantigen 1 isoform X2

      UniProtKB/TrEMBL
      F7GQ13
      Related
      ENSMMUP00000064392.1, ENSMMUT00000094764.1
      Conserved Domains (2) summary
      cd07661
      Location:52 → 255
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:261 → 483
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    5. XM_015133995.2 → XP_014989481.1  islet cell autoantigen 1 isoform X2

      UniProtKB/TrEMBL
      F7GQ13
      Conserved Domains (2) summary
      cd07661
      Location:52 → 255
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:261 → 483
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    6. XM_028844806.1 → XP_028700639.1  islet cell autoantigen 1 isoform X4

      UniProtKB/TrEMBL
      F7GQ13
      Conserved Domains (2) summary
      cd07661
      Location:52 → 255
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:261 → 462
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    7. XM_028844809.1 → XP_028700642.1  islet cell autoantigen 1 isoform X7

      UniProtKB/TrEMBL
      G7MLT2
      Related
      ENSMMUP00000061861.1, ENSMMUT00000082347.1
      Conserved Domains (2) summary
      cd07661
      Location:52 → 255
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:260 → 512
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    8. XM_028844808.1 → XP_028700641.1  islet cell autoantigen 1 isoform X6

      Conserved Domains (1) summary
      cl12013
      Location:53 → 194
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    9. XM_028844807.1 → XP_028700640.1  islet cell autoantigen 1 isoform X5

      UniProtKB/TrEMBL
      F7GQ13
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:261 → 445
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    10. XM_028844805.1 → XP_028700638.1  islet cell autoantigen 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZG78, F7GQ13
      Related
      ENSMMUP00000064596.1, ENSMMUT00000087226.1
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 463
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    11. XM_015133989.2 → XP_014989475.1  islet cell autoantigen 1 isoform X1

      UniProtKB/TrEMBL
      F7GQ13, I2CU09
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 484
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    12. XM_015133992.2 → XP_014989478.1  islet cell autoantigen 1 isoform X1

      UniProtKB/TrEMBL
      F7GQ13, I2CU09
      Related
      ENSMMUP00000080874.1, ENSMMUT00000087336.1
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 484
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    13. XM_015133996.2 → XP_014989482.1  islet cell autoantigen 1 isoform X2

      UniProtKB/TrEMBL
      F7GQ13
      Conserved Domains (2) summary
      cd07661
      Location:52 → 255
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:261 → 483
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    14. XM_015133990.2 → XP_014989476.1  islet cell autoantigen 1 isoform X1

      UniProtKB/TrEMBL
      F7GQ13, I2CU09
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 484
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    15. XM_028844804.1 → XP_028700637.1  islet cell autoantigen 1 isoform X1

      UniProtKB/TrEMBL
      F7GQ13, I2CU09
      Conserved Domains (2) summary
      cd07661
      Location:53 → 256
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 484
      ICA69; Islet cell autoantigen ICA69, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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