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    MARK2 microtubule affinity regulating kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718065, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MARK2provided by VGNC
    Official Full Name
    microtubule affinity regulating kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:74634
    See related
    Ensembl:ENSMMUG00000014131
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MARK2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (10646735..10722729, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (10656572..10733500, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene N-alpha-acetyltransferase 40, NatD catalytic subunit Neighboring gene REST corepressor 2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114672240 Neighboring gene spindlin interactor and repressor of chromatin binding Neighboring gene collagen alpha-1(I) chain-like Neighboring gene zinc finger translocation associated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tau-protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase MARK2
    XP_002799550.2
    XP_014969409.1
    XP_014969410.1
    XP_014969411.1
    XP_014969412.1
    XP_014969413.1
    XP_014969414.1
    XP_014969415.1
    XP_014969417.1
    XP_014969418.1
    XP_014969419.1
    XP_014969420.1
    XP_014969421.1
    XP_014969422.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      10646735..10722729 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015113923.2 → XP_014969409.1  serine/threonine-protein kinase MARK2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RDC4, F6TA28
      Related
      ENSMMUP00000037412.2, ENSMMUT00000044397.3
      Conserved Domains (3) summary
      cd12201
      Location:689 → 787
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    2. XM_015113936.2 → XP_014969422.1  serine/threonine-protein kinase MARK2 isoform X14

      UniProtKB/TrEMBL
      A0A1D5RDC4, H9Z659
      Related
      ENSMMUP00000054742.1, ENSMMUT00000053813.2
      Conserved Domains (3) summary
      cd12201
      Location:610 → 708
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    3. XM_015113934.2 → XP_014969420.1  serine/threonine-protein kinase MARK2 isoform X12

      UniProtKB/TrEMBL
      A0A1D5RDC4, F7C1D8, H9FR03
      Conserved Domains (3) summary
      cd12201
      Location:625 → 723
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    4. XM_015113935.2 → XP_014969421.1  serine/threonine-protein kinase MARK2 isoform X13

      UniProtKB/TrEMBL
      A0A1D5RDC4
      Conserved Domains (3) summary
      cd12201
      Location:620 → 718
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    5. XM_015113932.2 → XP_014969418.1  serine/threonine-protein kinase MARK2 isoform X10

      UniProtKB/TrEMBL
      A0A1D5RDC4
      Conserved Domains (3) summary
      cd12201
      Location:634 → 732
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    6. XM_015113924.2 → XP_014969410.1  serine/threonine-protein kinase MARK2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5RDC4, I0FPU4
      Conserved Domains (3) summary
      cd12201
      Location:688 → 786
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    7. XM_015113933.2 → XP_014969419.1  serine/threonine-protein kinase MARK2 isoform X11

      UniProtKB/TrEMBL
      A0A1D5RDC4
      Conserved Domains (3) summary
      cd12201
      Location:626 → 724
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    8. XM_015113931.2 → XP_014969417.1  serine/threonine-protein kinase MARK2 isoform X9

      UniProtKB/TrEMBL
      A0A1D5RDC4
      Conserved Domains (3) summary
      cd12201
      Location:635 → 733
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    9. XM_015113928.2 → XP_014969414.1  serine/threonine-protein kinase MARK2 isoform X6

      UniProtKB/TrEMBL
      A0A1D5RDC4
      Conserved Domains (3) summary
      cd12201
      Location:665 → 763
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    10. XM_015113925.2 → XP_014969411.1  serine/threonine-protein kinase MARK2 isoform X3

      UniProtKB/TrEMBL
      A0A1D5RDC4
      Conserved Domains (3) summary
      cd12201
      Location:680 → 778
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    11. XM_015113927.2 → XP_014969413.1  serine/threonine-protein kinase MARK2 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RDC4
      Conserved Domains (3) summary
      cd12201
      Location:674 → 772
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    12. XM_002799504.3 → XP_002799550.2  serine/threonine-protein kinase MARK2 isoform X8

      UniProtKB/TrEMBL
      A0A5K1U6E9
      Conserved Domains (3) summary
      cd12201
      Location:646 → 744
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289 → 330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19 → 271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    13. XM_015113926.2 → XP_014969412.1  serine/threonine-protein kinase MARK2 isoform X4

      UniProtKB/TrEMBL
      A0A1D5RDC4, F6TA54, F6TAM5, H9FR04
      Related
      ENSMMUP00000037410.3, ENSMMUT00000044395.3
      Conserved Domains (3) summary
      cd12201
      Location:679 → 777
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322 → 363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52 → 304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    14. XM_015113929.2 → XP_014969415.1  serine/threonine-protein kinase MARK2 isoform X7

      UniProtKB/TrEMBL
      A0A5K1U6E9
      Conserved Domains (3) summary
      cd12201
      Location:656 → 754
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289 → 330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19 → 271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    Nucleotide Protein
    Heading Accession and Version

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