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    ARHGEF7 Rho guanine nucleotide exchange factor 7 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695530, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGEF7provided by VGNC
    Official Full Name
    Rho guanine nucleotide exchange factor 7provided by VGNC
    Primary source
    VGNC:VGNC:69833
    See related
    Ensembl:ENSMMUG00000013138
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGEF7 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (92483366..92666605)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (92749302..92930551)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106994382 Neighboring gene uncharacterized LOC106994391 Neighboring gene testis expressed 29 Neighboring gene uncharacterized LOC106994393

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho guanine nucleotide exchange factor 7
    Names
    Rho guanine nucleotide exchange factor (GEF) 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      92483366..92666605
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028837335.1 → XP_028693168.1  rho guanine nucleotide exchange factor 7 isoform X12

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (5) summary
      cd12061
      Location:95 → 148
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:179 → 356
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:387 → 485
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16614
      Location:541 → 639
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      cl00030
      Location:3 → 89
      CH_SF; calponin homology (CH) domain superfamily

    2. XM_015121452.2 → XP_014976938.1  rho guanine nucleotide exchange factor 7 isoform X2

      UniProtKB/TrEMBL
      F6Q7V7, G7NJM5
      Related
      ENSMMUP00000018108.4, ENSMMUT00000019337.4
      Conserved Domains (8) summary
      cd12061
      Location:167 → 220
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00014
      Location:21 → 107
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00160
      Location:251 → 428
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:459 → 557
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam00169
      Location:477 → 557
      PH; PH domain
      pfam16523
      Location:773 → 859
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:613 → 711
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:117 → 163
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7

    3. XM_015121454.2 → XP_014976940.1  rho guanine nucleotide exchange factor 7 isoform X7

      UniProtKB/TrEMBL
      F6Z9L8, G7NJM5
      Related
      ENSMMUP00000017261.4, ENSMMUT00000018434.4
      Conserved Domains (8) summary
      cd12061
      Location:167 → 220
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00014
      Location:21 → 107
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00160
      Location:251 → 428
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:459 → 557
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam00169
      Location:477 → 557
      PH; PH domain
      pfam16523
      Location:714 → 800
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:613 → 711
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:117 → 163
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7

    4. XM_028837324.1 → XP_028693157.1  rho guanine nucleotide exchange factor 7 isoform X1

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (8) summary
      cd12061
      Location:167 → 220
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00014
      Location:21 → 107
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00160
      Location:251 → 428
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:459 → 587
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:803 → 889
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:643 → 741
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:117 → 163
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
      pfam03154
      Location:582 → 669
      Atrophin-1; Atrophin-1 family

    5. XM_028837325.1 → XP_028693158.1  rho guanine nucleotide exchange factor 7 isoform X3

      Conserved Domains (8) summary
      cd12061
      Location:167 → 220
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00014
      Location:21 → 107
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00160
      Location:251 → 428
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:459 → 587
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:744 → 830
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:643 → 741
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:117 → 163
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
      pfam03154
      Location:582 → 669
      Atrophin-1; Atrophin-1 family

    6. XM_028837327.1 → XP_028693160.1  rho guanine nucleotide exchange factor 7 isoform X5

      Conserved Domains (7) summary
      cd12061
      Location:167 → 220
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00014
      Location:21 → 107
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00160
      Location:251 → 428
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:459 → 587
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:728 → 814
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:606 → 666
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:117 → 163
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7

    7. XM_015121456.2 → XP_014976942.1  rho guanine nucleotide exchange factor 7 isoform X8

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (8) summary
      cd12061
      Location:167 → 220
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00014
      Location:21 → 107
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00160
      Location:251 → 428
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:459 → 557
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam00169
      Location:477 → 557
      PH; PH domain
      pfam16523
      Location:698 → 784
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:576 → 636
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:117 → 163
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7

    8. XM_028837326.1 → XP_028693159.1  rho guanine nucleotide exchange factor 7 isoform X4

      Conserved Domains (7) summary
      cd12061
      Location:95 → 148
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      smart00033
      Location:21 → 96
      CH; Calponin homology domain
      cd00160
      Location:179 → 356
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:387 → 515
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:731 → 817
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:571 → 669
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam03154
      Location:510 → 597
      Atrophin-1; Atrophin-1 family

    9. XM_028837334.1 → XP_028693167.1  rho guanine nucleotide exchange factor 7 isoform X10

      Conserved Domains (7) summary
      cd12061
      Location:95 → 148
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:179 → 356
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:387 → 485
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:642 → 728
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:541 → 639
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam00307
      Location:5 → 97
      CH; Calponin homology (CH) domain
      pfam03154
      Location:480 → 567
      Atrophin-1; Atrophin-1 family

    10. XM_028837330.1 → XP_028693163.1  rho guanine nucleotide exchange factor 7 isoform X9

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (6) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 430
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:646 → 732
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:486 → 584
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam03154
      Location:425 → 512
      Atrophin-1; Atrophin-1 family

    11. XM_028837331.1 → XP_028693164.1  rho guanine nucleotide exchange factor 7 isoform X9

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (6) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 430
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:646 → 732
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:486 → 584
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam03154
      Location:425 → 512
      Atrophin-1; Atrophin-1 family

    12. XM_028837329.1 → XP_028693162.1  rho guanine nucleotide exchange factor 7 isoform X9

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (6) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 430
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:646 → 732
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:486 → 584
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam03154
      Location:425 → 512
      Atrophin-1; Atrophin-1 family

    13. XM_028837338.1 → XP_028693171.1  rho guanine nucleotide exchange factor 7 isoform X16

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (4) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 400
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16614
      Location:456 → 554
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7

    14. XM_015121461.2 → XP_014976947.1  rho guanine nucleotide exchange factor 7 isoform X13

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (5) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 400
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16614
      Location:456 → 554
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16523
      Location:616 → 702
      betaPIX_CC; betaPIX coiled coil

    15. XM_015121462.2 → XP_014976948.1  rho guanine nucleotide exchange factor 7 isoform X14

      Conserved Domains (5) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 400
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16614
      Location:456 → 554
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16523
      Location:557 → 643
      betaPIX_CC; betaPIX coiled coil

    16. XM_028837336.1 → XP_028693169.1  rho guanine nucleotide exchange factor 7 isoform X14

      Conserved Domains (5) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 400
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16614
      Location:456 → 554
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16523
      Location:557 → 643
      betaPIX_CC; betaPIX coiled coil

    17. XM_028837328.1 → XP_028693161.1  rho guanine nucleotide exchange factor 7 isoform X6

      UniProtKB/TrEMBL
      G7NJM5
      Related
      ENSMMUP00000036019.3, ENSMMUT00000043004.3
      Conserved Domains (7) summary
      cd12061
      Location:85 → 138
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:169 → 346
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:377 → 505
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:721 → 807
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:561 → 659
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:35 → 81
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
      pfam03154
      Location:500 → 587
      Atrophin-1; Atrophin-1 family

    18. XM_015121459.2 → XP_014976945.1  rho guanine nucleotide exchange factor 7 isoform X11

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (7) summary
      cd12061
      Location:85 → 138
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:169 → 346
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:377 → 475
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam00169
      Location:395 → 475
      PH; PH domain
      pfam16523
      Location:632 → 718
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:531 → 629
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16615
      Location:35 → 81
      RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7

    19. XM_028837332.1 → XP_028693165.1  rho guanine nucleotide exchange factor 7 isoform X9

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (6) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 430
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:646 → 732
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:486 → 584
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam03154
      Location:425 → 512
      Atrophin-1; Atrophin-1 family

    20. XM_028837333.1 → XP_028693166.1  rho guanine nucleotide exchange factor 7 isoform X9

      UniProtKB/TrEMBL
      G7NJM5
      Conserved Domains (6) summary
      cd12061
      Location:10 → 63
      SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
      cd00160
      Location:94 → 271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:302 → 430
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16523
      Location:646 → 732
      betaPIX_CC; betaPIX coiled coil
      pfam16614
      Location:486 → 584
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam03154
      Location:425 → 512
      Atrophin-1; Atrophin-1 family

    21. XM_028837337.1 → XP_028693170.1  rho guanine nucleotide exchange factor 7 isoform X15

      Conserved Domains (4) summary
      cd00160
      Location:16 → 193
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01225
      Location:224 → 322
      PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
      pfam16614
      Location:378 → 476
      RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
      pfam16523
      Location:538 → 624
      betaPIX_CC; betaPIX coiled coil

    RNA

    1. XR_003724217.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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