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    PLCD3 phospholipase C delta 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715924, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLCD3provided by VGNC
    Official Full Name
    phospholipase C delta 3provided by VGNC
    Primary source
    VGNC:VGNC:99205
    See related
    Ensembl:ENSMMUG00000013587
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLCD3 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (56372938..56395851, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (51030211..51054192, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene dephospho-CoA kinase domain containing Neighboring gene N-myristoyltransferase 1 Neighboring gene acyl-CoA binding domain containing 4 Neighboring gene HEXIM P-TEFb complex subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
    XP_001115230.1
    XP_014975388.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      56372938..56395851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001115230.4 → XP_001115230.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1

      UniProtKB/TrEMBL
      F7GU82, G7NJ45
      Related
      ENSMMUP00000017861.4, ENSMMUT00000019071.4
      Conserved Domains (7) summary
      cd00275
      Location:656 → 783
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08630
      Location:332 → 627
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:251 → 785
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:61 → 177
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam00169
      Location:66 → 166
      PH; PH domain
      pfam09279
      Location:251 → 332
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
      pfam14788
      Location:197 → 246
      EF-hand_10; EF hand

    2. XM_015119902.2 → XP_014975388.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X2

      UniProtKB/TrEMBL
      G7NJ45
      Conserved Domains (7) summary
      cd00275
      Location:615 → 742
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08630
      Location:291 → 586
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:210 → 744
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam00169
      Location:25 → 125
      PH; PH domain
      pfam09279
      Location:210 → 291
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
      pfam14788
      Location:156 → 205
      EF-hand_10; EF hand
    Nucleotide Protein
    Heading Accession and Version

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