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    CTSS cathepsin S [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708080, updated on 17-Aug-2024

    Summary

    Official Symbol
    CTSSprovided by VGNC
    Official Full Name
    cathepsin Sprovided by VGNC
    Primary source
    VGNC:VGNC:71562
    Locus tag
    EGK_01236
    See related
    Ensembl:ENSMMUG00000010670
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See CTSS in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (100364074..100400316)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (125191416..125227663, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene aryl hydrocarbon receptor nuclear translocator Neighboring gene U6 spliceosomal RNA Neighboring gene cathepsin K Neighboring gene HORMA domain containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene golgi phosphoprotein 3 like

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      100364074..100400316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151744.2XP_015007230.1  cathepsin S isoform X1

      UniProtKB/TrEMBL
      A0A5F8AB19, A0A8J8XL63, F7B4I9, G7MDI2
      Related
      ENSMMUP00000074118.1, ENSMMUT00000096664.1
      Conserved Domains (3) summary
      PTZ00203
      Location:5326
      PTZ00203; cathepsin L protease; Provisional
      smart00848
      Location:2887
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:115329
      Peptidase_C1; Papain family cysteine protease
    2. XM_028829281.1XP_028685114.1  cathepsin S isoform X2

      UniProtKB/TrEMBL
      F7B4I9
      Conserved Domains (2) summary
      smart00848
      Location:346
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      cd02248
      Location:75288
      Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...