These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001320501.1 → NP_001307430.1  protein argonaute-1 isoform 1

   Status: REVIEWED

   Description

   Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (1) results from translation termination at the upstream UGA stop codon, while the longer isoform (1x) results from UGA stop codon readthrough to the downstream UAG termination codon. This RefSeq represents the shorter isoform (1).

   Source sequence(s)

   JU475150, JV540982, JV578265

   UniProtKB/TrEMBL

   A0A1D5R8N4, F7H593, H9FSW2

   Related

   ENSMMUP00000056674.2, ENSMMUT00000067719.2

   Conserved Domains (4) summary

   cd02846
   Location:225 → 345

   PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...

   cd04657
   Location:390 → 815

   Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...

   pfam08699
   Location:174 → 224

   ArgoL1; Argonaute linker 1 domain

   pfam16486
   Location:34 → 164

   ArgoN; N-terminal domain of argonaute

2. NM_001320502.1 → NP_001307431.1  protein argonaute-1 isoform 1x

   Status: REVIEWED

   Description

   Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (1) results from translation termination at the upstream UGA stop codon, while the longer isoform (1x) results from UGA stop codon readthrough to the downstream UAG termination codon. This RefSeq represents the longer, C-terminally extended isoform (1x). As the UGA stop codon has been reported to specify several alternative amino acids (tryptophan, cysteine, arginine and serine), its location in the longer isoform is denoted by an 'X'.

   Source sequence(s)

   JU475150, JV540982, JV578265

   UniProtKB/TrEMBL

   F7H593

   Conserved Domains (5) summary

   PLN03202
   Location:26 → 856

   PLN03202; protein argonaute; Provisional

   cd02846
   Location:225 → 345

   PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...

   cd04657
   Location:390 → 815

   Piwi_ago-like; Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of ...

   pfam08699
   Location:175 → 224

   ArgoL1; Argonaute linker 1 domain

   pfam16486
   Location:26 → 164

   ArgoN; N-terminal domain of argonaute

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference Mmul_10 Primary Assembly

Genomic

1. NC_041754.1 Reference Mmul_10 Primary Assembly

   Range

   188673810..188715517 complement

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)