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    TLK1 tousled like kinase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694298, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TLK1provided by VGNC
    Official Full Name
    tousled like kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:78367
    See related
    Ensembl:ENSMMUG00000011189
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TLK1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (58131221..58298506, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (58027070..58193412, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene golgi reassembly stacking protein 2 Neighboring gene uncharacterized LOC114671351 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC106992612 Neighboring gene small integral membrane protein 26-like Neighboring gene uncharacterized LOC114671354 Neighboring gene methyltransferase 8, tRNA N3-cytidine

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase tousled-like 1
    XP_014965838.1
    XP_014965839.1
    XP_028686667.1
    XP_028686668.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      58131221..58298506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028830834.1 → XP_028686667.1  serine/threonine-protein kinase tousled-like 1 isoform X1

      UniProtKB/TrEMBL
      F6V0L3, H9EPW6
      Related
      ENSMMUP00000014666.4, ENSMMUT00000015657.4
      Conserved Domains (2) summary
      COG1196
      Location:209 → 454
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd14040
      Location:449 → 747
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    2. XM_015110352.2 → XP_014965838.1  serine/threonine-protein kinase tousled-like 1 isoform X2

      Conserved Domains (2) summary
      smart00220
      Location:443 → 710
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14040
      Location:425 → 723
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    3. XM_028830835.1 → XP_028686668.1  serine/threonine-protein kinase tousled-like 1 isoform X3

      Conserved Domains (1) summary
      cd14040
      Location:401 → 699
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1

    4. XM_015110353.2 → XP_014965839.1  serine/threonine-protein kinase tousled-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A1D5RC70
      Conserved Domains (2) summary
      smart00220
      Location:371 → 638
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14040
      Location:353 → 651
      STKc_TLK1; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 1
    Nucleotide Protein
    Heading Accession and Version

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