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    SPO11 SPO11 initiator of meiotic double strand breaks [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696836, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPO11provided by VGNC
    Official Full Name
    SPO11 initiator of meiotic double strand breaksprovided by VGNC
    Primary source
    VGNC:VGNC:108061
    See related
    Ensembl:ENSMMUG00000050707
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPO11 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (92493818..92508365)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (7069469..7085664, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 7 Neighboring gene uncharacterized LOC107000351 Neighboring gene uncharacterized LOC114670509 Neighboring gene MT-RNR2 like 3 Neighboring gene ribonucleic acid export 1 Neighboring gene RNA binding motif protein 38

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in meiotic DNA double-strand break formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in meiotic DNA double-strand break processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in reciprocal meiotic recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear chromosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    meiotic recombination protein SPO11
    Names
    SPO11 initiator of meiotic double stranded breaks
    SPO11 meiotic protein covalently bound to DSB homolog
    XP_001088572.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      92493818..92508365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001088572.4 → XP_001088572.2  meiotic recombination protein SPO11

      UniProtKB/TrEMBL
      F6X9S4, G7N4G6
      Related
      ENSMMUP00000000347.3, ENSMMUT00000000370.4
      Conserved Domains (2) summary
      COG1697
      Location:43 → 391
      Spo11; DNA topoisomerase VI, subunit A [Replication, recombination and repair]
      pfam03533
      Location:2 → 44
      SPO11_like; SPO11 homolog
    Nucleotide Protein
    Heading Accession and Version

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